Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201374
Type: Artigo de periódico
Title: Adapting The Sniffin' Sticks Olfactory Test To Diagnose Parkinson's Disease In Estonia.
Author: Antsov, Eva
Silveira-Moriyama, Laura
Kilk, Stela
Kadastik-Eerme, Liis
Toomsoo, Toomas
Lees, Andrew
Taba, Pille
Abstract: The aim of the study was to develop a culturally adapted translation of the 12-item smell identification test from Sniffin' Sticks (SS-12) for the Estonian population in order to help diagnose Parkinson's disease (PD). A standard translation of the SS-12 was created and 150 healthy Estonians were questioned about the smells used as response options in the test. Unfamiliar smells were replaced by culturally familiar options. The adapted SS-12 was applied to 70 controls in all age groups, and thereafter to 50 PD patients and 50 age- and sex-matched controls. 14 response options from 48 used in the SS-12 were replaced with familiar smells in an adapted version, in which the mean rate of correct response was 87% (range 73-99) compared to 83% with the literal translation (range 50-98). In PD patients, the average adapted SS-12 score (5.4/12) was significantly lower than in controls (average score 8.9/12), p < 0.0001. A multiple linear regression using the score in the SS-12 as the outcome measure showed that diagnosis and age independently influenced the result of the SS-12. A logistic regression using the SS-12 and age as covariates showed that the SS-12 (but not age) correctly classified 79.0% of subjects into the PD and control category, using a cut-off of <7 gave a sensitivity of 76% and specificity of 86% for the diagnosis of PD. The developed SS-12 cultural adaption is appropriate for testing olfaction in Estonia for the purpose of PD diagnosis.
Subject: Cultural Adaption
Olfactory Dysfunction
Parkinson's Disease
Smell Test
Sniffin' Sticks
Rights: fechado
Identifier DOI: 10.1016/j.parkreldis.2014.04.012
Address: http://www.ncbi.nlm.nih.gov/pubmed/24792992
Date Issue: 2014
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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