Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201321
Type: Artigo de periódico
Title: Proteomics, Metabolomics, And Protein Interactomics In The Characterization Of The Molecular Features Of Major Depressive Disorder.
Author: Martins-de-Souza, Daniel
Abstract: Omics technologies emerged as complementary strategies to genomics in the attempt to understand human illnesses. In general, proteomics technologies emerged earlier than those of metabolomics for major depressive disorder (MDD) research, but both are driven by the identification of proteins and/or metabolites that can delineate a comprehensive characterization of MDD's molecular mechanisms, as well as lead to the identification of biomarker candidates of all types-prognosis, diagnosis, treatment, and patient stratification. Also, one can explore protein and metabolite interactomes in order to pinpoint additional molecules associated with the disease that had not been picked up initially. Here, results and methodological aspects of MDD research using proteomics, metabolomics, and protein interactomics are reviewed, focusing on human samples.
Subject: Animals
Depressive Disorder, Major
Humans
Metabolomics
Proteomics
Csf
Nmr
Biomarker
Blood
Brain
Depression
Interactomics
Major Depression
Mass Spectrometry
Metabolomics
Proteomics
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/24733971
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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