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Type: Artigo de periódico
Title: Analysis Of The Effect Of Renal Excretory System Cooling During Thermal Radiofrequency Ablation In An Animal Model.
Author: Meireles, André
Taha, Khaled Ahmed Neto
Castilho, Lísias Nogueira
D'Ippolito, Giuseppe
Reis, Leonardo Oliveira
Abstract: Analysis of renal excretory system integrity and efficacy of radiofrequency ablation with and without irrigation with saline at 2°C (SF2). The median third of sixteen kidneys were submitted to radiofrequency (exposition of 1 cm) controlled by intra-surgical ultrasound, with eight minutes cycles and median temperature of 90°C in eight female pigs. One excretory renal system was cooled with SF2, at a 30mL/min rate, and the other kidney was not. After 14 days of post-operatory, the biggest diameters of the lesions and the radiological aspects of the excretory system were compared by bilateral ascending pyelogram and the animals were sacrificed in order to perform histological analysis. There were no significant differences between the diameters of the kidney lesions whether or not exposed to cooling of the excretory system. Median diameter of the cooled kidneys and not cooled kidneys were respectively (in mm): anteroposterior: 11.46 vs. 12.5 (p = 0.23); longitudinal: 17.94 vs. 18.84 (p = 0.62); depth: 11.38 vs. 12.25 (p = 0.47). There was no lesion of the excretory system or signs of leakage of contrast media or hydronephrosis at ascending pyelogram. Cooling of excretory system during radiofrequency ablation does not sig¬nificantly alter generated coagulation necrosis or affect the integrity of the excretory system in the studied model.
Subject: Animals
Catheter Ablation
Cold Temperature
Models, Animal
Organ Size
Reference Values
Reproducibility Of Results
Saline Solution, Hypertonic
Therapeutic Irrigation
Time Factors
Ultrasonography, Interventional
Rights: aberto
Identifier DOI: 
Date Issue: -1-Uns- -1
Appears in Collections:Unicamp - Artigos e Outros Documentos

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