Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201225
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleTribulus Terrestris Versus Placebo In The Treatment Of Erectile Dysfunction: A Prospective, Randomized, Double Blind Study.pt_BR
dc.contributor.authorSantos, C Apt_BR
dc.contributor.authorReis, L Opt_BR
dc.contributor.authorDestro-Saade, Rpt_BR
dc.contributor.authorLuiza-Reis, Apt_BR
dc.contributor.authorFregonesi, Apt_BR
unicamp.authorC A Santos, Departamento de Cirugía (Urología), Facultad de Ciencias Médicas, Universidad Estatal de Campinas UNICAMP, São Paulo, Brasil.pt_BR
unicamp.authorL O Reis, Departamento de Cirugía (Urología), Facultad de Ciencias Médicas, Universidad Estatal de Campinas UNICAMP, São Paulo, Brasilpt_BR
unicamp.authorFacultad de Medicina (Urología), Centro de Ciencias de la Vida, Universidad Católica de Campinas PUC-Campinas, São Paulo, Brasil. Electronic address: reisleo@unicamp.br.pt_BR
unicamp.authorR Destro-Saade, Departamento de Cirugía (Urología), Facultad de Ciencias Médicas, Universidad Estatal de Campinas UNICAMP, São Paulo, Brasil.pt_BR
unicamp.authorA Luiza-Reis, Departamento de Cirugía (Urología), Facultad de Ciencias Médicas, Universidad Estatal de Campinas UNICAMP, São Paulo, Brasil.pt_BR
unicamp.authorA Fregonesi, Departamento de Cirugía (Urología), Facultad de Ciencias Médicas, Universidad Estatal de Campinas UNICAMP, São Paulo, Brasil.pt_BR
dc.subjectAlternative Medicinept_BR
dc.subjectDisfunción Sexualpt_BR
dc.subjectFitoterapiapt_BR
dc.subjectHerbal Medicinept_BR
dc.subjectImpotencept_BR
dc.subjectImpotenciapt_BR
dc.subjectLibidopt_BR
dc.subjectMedicina Alternativapt_BR
dc.subjectPlacebo And Chinese Medicinept_BR
dc.subjectPlacebo Y Medicina Chinapt_BR
dc.subjectSexual Dysfunctionpt_BR
dc.subjectTestosteronapt_BR
dc.subjectTestosteronept_BR
dc.description.abstractTo evaluate the possible effects of Tribulus terrestris herbal medicine in the erectile dysfunction treatment and to quantify its potential impact on serum testosterone levels. Prospective, randomized, double-blind and placebo-controlled study including thirty healthy men selected from 100 patients who presented themselves spontaneously complaining of erectile dysfunction, ≥ 40 years of age, nonsmokers, not undergoing treatment for prostate cancer or erectile dysfunction, no dyslipidemia, no phosphodiesterase inhibitor use, no hormonal manipulation and, if present hypertension and/or diabetes mellitus should be controlled. International Index of Erectile Function (IIEF-5) and serum testosterone were obtained before randomization and after 30 days of study. Patients were randomized into two groups of fifteen subjects each. The study group received 800 mg of Tribulus terrestris, divided into two doses per day for thirty days and the control group received placebo administered in the same way. The groups were statistically equivalent in all aspects evaluated. The mean (SD) age was 60 (9.4) and 62.9 (7.9), P = .36 for intervention and placebo groups, respectively. Before treatment, the intervention group showed mean IIEF-5 of 13.2 (5-21) and mean total testosterone 417.1 ng/dl (270.7-548.4 ng/dl); the placebo group showed mean IIEF-5 of 11.6 (6-21) and mean total testosterone 442.7 ng/dl (301-609.1 ng/dl). After treatment, the intervention group showed mean IIEF-5 of 15.3 (5-21) and mean total testosterone 409.3 ng/dl (216.9-760.8 ng/dl); the placebo group showed mean IIEF-5 of 13.7 (6-21) and mean total testosterone 466.3 ng/dl (264.3-934.3 ng/dl). The time factor caused statistically significant changes in both groups for IIEF-5 only (P = .0004), however, there was no difference between the two groups (P = .7914). At the dose and interval studied, Tribulus terrestris was not more effective than placebo on improving symptoms of erectile dysfunction or serum total testosterone.en
dc.relation.ispartofActas Urologicas Españolaspt_BR
dc.relation.ispartofabbreviationActas Urol Esppt_BR
dc.date.issued2014-Maypt_BR
dc.identifier.citationActas Urologicas Españolas. v. 38, n. 4, p. 244-8, 2014-May.pt_BR
dc.language.isoengpt_BR
dc.language.isospapt_BR
dc.description.volume38pt_BR
dc.description.firstpage244-8pt_BR
dc.rightsfechadopt_BR
dc.rights.holderCopyright © 2013 AEU. Published by Elsevier Espana. All rights reserved.pt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1699-7980pt_BR
dc.identifier.doi10.1016/j.acuro.2013.09.014pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/24630840pt_BR
dc.date.available2015-11-27T13:42:07Z-
dc.date.accessioned2015-11-27T13:42:07Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:42:07Z (GMT). No. of bitstreams: 1 pmed_24630840.pdf: 448588 bytes, checksum: 126ab8eb90fa2b7280c5746f6c4176b6 (MD5) Previous issue date: 2014en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/201225-
dc.identifier.idPubmed24630840pt_BR
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_24630840.pdf438.07 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.