Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201143
Type: Artigo
Title: Synchronous antiresorptive osteonecrosis of the jaws and breast cancer metastasis
Author: Flores, Isadora Luana
dos Santos-Silva, Alan Roger
Della Coletta, Ricardo
Vargas, Pablo Agustin
Lopes, Márcio Ajudarte
Abstract: Antiresorptive osteonecrosis of the jaws (ARONJ) is a significant and poorly understood oral complication that may affect patients receiving antiresorptive agents, such as intravenous bisphosphonate therapy. There are scarce reports of the coexistence of ARONJ and metastasis at the same jaw site in the English-language literature. In the present case, a 60-year-old white woman was referred for the evaluation of a nonhealing extraction socket. The patient was undergoing treatment with intravenous zoledronic acid to metastatic breast cancer in bone, and her medical history and clinical characteristics led to the diagnosis of ARONJ. Nevertheless, histologic analysis showed a fragment of necrotic bone and bacterial colonies associated with malignant epithelial cells that were confirmed to be metastatic breast adenocarcinoma. This case showed that jaw metastasis can occur at the same time and site of ARONJ, making diagnosis and management challenging.
Antiresorptive osteonecrosis of the jaws (ARONJ) is a significant and poorly understood oral complication that may affect patients receiving antiresorptive agents, such as intravenous bisphosphonate therapy. There are scarce reports of the coexistence of ARONJ and metastasis at the same jaw site in the English-language literature. In the present case, a 60-year-old white woman was referred for the evaluation of a nonhealing extraction socket. The patient was undergoing treatment with intravenous zoledronic acid to metastatic breast cancer in bone, and her medical history and clinical characteristics led to the diagnosis of ARONJ. Nevertheless, histologic analysis showed a fragment of necrotic bone and bacterial colonies associated with malignant epithelial cells that were confirmed to be metastatic breast adenocarcinoma. This case showed that jaw metastasis can occur at the same time and site of ARONJ, making diagnosis and management challenging
Subject: Neoplasias maxilomandibulares
Country: Holanda
Editor: Elsevier
Citation: Oral Surgery, Oral Medicine, Oral Pathology And Oral Radiology. v. 117, n. 3, p. e264-8, 2014-Mar.
Rights: fechado
Identifier DOI: 10.1016/j.oooo.2013.11.495
Address: https://www.sciencedirect.com/science/article/pii/S2212440313016805
Date Issue: 2014
Appears in Collections:FOP - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
24528798.pdf1.49 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.