Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201137
Type: Artigo de periódico
Title: Serum Antibodies To Pseudomonas Aeruginosa In Cystic Fibrosis As A Diagnostic Tool: A Systematic Review.
Author: Mauch, Renan Marrichi
Levy, Carlos Emilio
Abstract: A systematic literature review of the last 40 years on the research of serum antibodies to Pseudomonas aeruginosa in cystic fibrosis and its utility as a diagnostic tool. Research papers in English, Portuguese, and Spanish were accessed through electronic databases (PubMed, Medline, LILACS, and SciELO). 26 studies were assessed. ELISA technique was the most commonly used technique to detect serum P. aeruginosa antibodies. The most consistent results were those in which the response against the antigen St-Ag:1-17 was evaluated. The accuracy levels of the ELISA technique remain controversial, but most studies showed a good correlation between antibody titers and microbiological culture. The detection of serum antibodies to P. aeruginosa shows capacity for early detection of this pathogen and potential utility and viability of incorporation in the diagnostic routine of patients with cystic fibrosis.
Subject: Cystic Fibrosis
Pseudomonas Aeruginosa
Review
Serum Antibodies
Rights: fechado
Identifier DOI: 10.1016/j.jcf.2014.01.005
Address: http://www.ncbi.nlm.nih.gov/pubmed/24522086
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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