Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200925
Type: Artigo de periódico
Title: Investigation Of Magnetic Resonance Imaging Texture Analysis As An Aid Tool For Characterization Of Refractory Epilepsies.
Author: Baldissin, Maurício Martins
Souza, Edna Marina de
Abstract: Refractory epilepsies are syndromes for which therapies that employ two or more antiepileptic drugs, separately or in association, do not result in control of crisis. Patients may present focal cortical dysplasia or diffuse dysplasia and/or hippocampal atrophic alterations that may not be detectable by a simple visual analysis in magnetic resonance imaging. The aim of this study was to evaluate MRI texture in regions of interest located in the hippocampi, limbic association cortex and prefrontal cortex of 20 patients with refractory epilepsy and to compare them with the same areas in 20 healthy individuals, in order to find out if the texture parameters could be related to the presence of the disease. Of the 11 texture parameters calculated, three indicated the existence of statistically significant differences between the studied groups. Such findings suggest the possibility of this technique contributing to studies of refractory epilepsies.
Subject: Adult
Atrophy
Case-control Studies
Epilepsy
Hippocampus
Humans
Magnetic Resonance Imaging
Malformations Of Cortical Development
Middle Aged
Retrospective Studies
Young Adult
Rights: aberto
Identifier DOI: 10.1590/0004-282X20130219
Address: http://www.ncbi.nlm.nih.gov/pubmed/24347009
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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