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Type: Artigo de periódico
Title: Immunochemical Fecal Occult Blood Test For Detection Of Advanced Colonic Adenomas And Colorectal Cancer: Comparison With Colonoscopy Results.
Author: Viana Freitas, Bianca Rosa
Kibune Nagasako, Cristiane
Pavan, Celia Regina
Silva Lorena, Sônia Letícia
Guerrazzi, Fabio
Saddy Rodrigues Coy, Cláudio
Ayrizono, Maria de Lourdes S
Mesquita, Maria Aparecida
Abstract: Background. Fecal immunochemical tests (FITs) have been used for colorectal cancer (CRC) screening in several countries. There is lack of information concerning diagnostic performances of this method in Brazil. Methods. Patients scheduled for elective colonoscopy provided one stool sample one week before colonoscopy. The accuracy of a qualitative FIT for detection of CRC and advanced adenomas was determined. Results. Overall 302 patients completed the study. Among them, 53.5% were high risk patients referred for screening or surveillance. Nine (3%) CRCs and 11 (3.6%) advanced adenomas were detected by colonoscopy. Sensitivity and specificity for CRC were, respectively, 88.9% and 87.6%. For advanced adenomas, sensitivity was 63.6% and specificity 87.6%. Conclusion. Our results showed good sensitivity and specificity of the FIT for detecting advanced neoplasias. This method may be a valuable tool for future screening programs in Brazil.
Citation: Gastroenterology Research And Practice. v. 2013, p. 384561, 2013.
Rights: aberto
Identifier DOI: 10.1155/2013/384561
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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