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Type: Artigo de periódico
Title: The White Coat Effect Is Not Associated With Additional Increase Of Target Organ Damage In True Resistant Hypertension.
Author: Figueiredo, Valéria Nasser
Martins, Luiz Cláudio
Boer-Martins, Leandro
Cabral de Faria, Ana Paula
de Haro Moraes, Carolina
Cardoso Santos, Rodrigo
Nogueira, Armando R
Moreno, Heitor
Abstract: White coat effect (WCE) (i.e., the difference between office blood pressure [OBP] and awake ambulatory blood pressure monitoring [ABPM]) may be present in hypertensive individuals. The relationship between occurrence of WCE and target organ damage (TOD) has not yet been assessed in true resistant hypertension (RHTN). RHTN patients were divided into two groups: RHTN with WCE (WCE, n=66) and RHTN without WCE (non-WCE, n=61). All patients were submitted to OBP measurement, ABPM, echocardiography and renal function evaluation in three visits. No differences were observed between the WCE and non-WCE groups regarding age, body mass index or gender. OBP were 169.8±15.8/95.1±14.0 (WCE) and 161.9±9.0/90.1±10.4mmHg (non-WCE), ABPM=143.0±12.8/86.1±9.9 (WCE) and 146.1±13.6/85.1±14.9mmHg (non-WCE). No statistical differences were observed between WCE and non-WCE subgroups with respect to left ventricular mass index (LVMI) (WCE=131±4.7; non-WCE=125±2.9g/m(2)), creatinine clearance (WCE=78±4.7; non-WCE=80±3.6ml/min/m(2)) and microalbuminuria (MA) (WCE=44±8.4; non-WCE=49±6.8mg/g Cr). This finding may suggest that WCE is not associated with additional increase of TOD in true RHTN subjects.
Subject: Aged
Antihypertensive Agents
Blood Pressure Determination
Blood Pressure Monitoring, Ambulatory
Combined Modality Therapy
Diet, Sodium-restricted
Drug Resistance
Drug Therapy, Combination
Hypertrophy, Left Ventricular
Middle Aged
Single-blind Method
White Coat Hypertension
Rights: fechado
Identifier DOI: 10.1016/j.medcli.2012.04.031
Date Issue: 2013
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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