Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200698
Type: Artigo de periódico
Title: Mass Spectrometry Made Easy: The Quest For Simplicity.
Author: Schwab, Nicolas V
Eberlin, Marcos N
Abstract: Mass spectrometry (MS) is generally viewed as a highly complex and demanding technique, full of difficulties and apprehensions. Ease and simplicity have been infrequently used descriptors of MS but a series of revolutionary developments is turning a complex technique into a model of simplicity, making MS easier than ever. Focusing on spray-based ambient desorption/ionization techniques, we discuss how previously unthinkable goals for MS - (1) to bring it to a real world open atmosphere environment; (2) to perform fast, selective, and highly sensitive chemical and biochemical MS analysis with ease while (3) avoiding pre-separation and sample work-up for samples in their natural environment and therefore, at the end, (4) to make MS accessible in wherever MS is needed and by whoever needs it - have become feasible. Without compromising the unique combination of high speed, selectivity, sensitivity and separation competences, simplicity has become a new MS attribute - a fifth 'S' in the unique 5 S set of MS trademark features.
Subject: Electricity
Equipment Design
Mass Spectrometry
Miniaturization
Pharmaceutical Preparations
Spectrometry, Mass, Electrospray Ionization
Vacuum
Rights: fechado
Identifier DOI: 10.1002/dta.1408
Address: http://www.ncbi.nlm.nih.gov/pubmed/22991334
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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