Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200461
Type: Artigo de periódico
Title: Texture Analysis Of Magnetic Resonance Images Of Patients With Juvenile Myoclonic Epilepsy.
Author: de Oliveira, Márcia Silva
Betting, Luiz Eduardo
Mory, Suzana B
Cendes, Fernando
Castellano, Gabriela
Abstract: Juvenile myoclonic epilepsy (JME) is the most frequent subsyndrome of the idiopathic generalized epilepsies, and experimental investigations support that the thalamus is a key structure in the mechanisms of JME. Texture analysis (TA) is an image processing technique which can be used to characterize images such as MRI. The goal of this work was to investigate the thalamus of patients with JME using TA, a quantitative neuroimaging technique. Patients and controls were submitted to MRI investigation. Images were acquired in a 2-Tesla scanner. The T1 volumetric sequence was used for thalamic segmentation and extraction of texture parameters. Twenty-four patients with a diagnosis of JME and 20 healthy volunteers were investigated. Texture analysis revealed differences between the right thalamus of patients and controls. The present investigation supports the participation of the thalamus in the disease mechanisms of JME. Texture analysis may be a useful tool in the quantitative neuroimaging investigation of the epilepsies and can be important to understand JME.
Subject: Adult
Brain
Brain Mapping
Contrast Media
Female
Fourier Analysis
Humans
Image Processing, Computer-assisted
Magnetic Resonance Imaging
Male
Middle Aged
Myoclonic Epilepsy, Juvenile
Sensitivity And Specificity
Young Adult
Rights: fechado
Identifier DOI: 10.1016/j.yebeh.2012.12.009
Address: http://www.ncbi.nlm.nih.gov/pubmed/23357730
Date Issue: 2013
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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