Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200453
Type: Artigo de periódico
Title: Reactive Post-radiotherapy Bone Formation In The Maxilla.
Author: Mariano, Fernanda Viviane
Gondak, Rogério Oliveira
Santos-Silva, Alan Roger
Corrêa, Marcelo Brum
Almeida, Oslei Paes de
Lopes, Márcio Ajudarte
Abstract: High-dose radiation therapy affects bone metabolism, and therefore post-radiotherapy bone formation is an uncommon finding. This case describes an unusual ossification in the maxillary region identified after head and neck radiotherapy. A 45-year-old female patient was submitted to maxillary surgical resection and orbital exenteration due to squamous cell carcinoma. Radiotherapy post-surgery was performed because of compromised surgical margins. After 4 months of the conclusion of radiotherapy, the patient presented a bone exposition at surgical site. Surprisingly, the oral examination and computed tomography revealed a new formation of the right palatine vault and bone formation filling the nasal and orbital cavity. The incisional biopsy discarded residual disease or osteoradionecrosis and showed normal tissue. To the best of the authors' knowledge, this is the first case of wide bone formation as an early effect of head and neck radiotherapy.
Subject: Biopsy
Carcinoma, Squamous Cell
Combined Modality Therapy
Female
Humans
Maxillary Sinus Neoplasms
Middle Aged
Orbital Neoplasms
Osteogenesis
Tomography, X-ray Computed
Rights: fechado
Identifier DOI: 10.1097/SCS.0b013e31826d0015
Address: http://www.ncbi.nlm.nih.gov/pubmed/23348333
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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