Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200317
Type: Artigo de periódico
Title: Associated Factors With Survivals In Patients Undergoing Orthotopic Heart Transplant Using Retrograde Blood Microcardioplegia.
Author: Lavagnoli, Carlos Fernando Ramos
Severino, Elaine Soraya Barbosa de Oliveira
Vilarinho, Karlos Alexandre de Souza
Silveira Filho, Lindemberg da Mota
Oliveira, Pedro Paulo Martins de
Petrucci, Orlando
Vieira, Reinaldo Wilson
Braile, Domingo Marcolino
Abstract: Several techniques and cardioplegic solutions have been used for heart preservation during transplant procedures. Unfortunately, there is a lack of ideal method for myocardial preservation in the clinical practice. The use of retrograde cardioplegia provides continuous infusion of cardioplegic solution during the graft implantation. This strategy may provide better initial recovery of the graft. The objective of this study is to describe the experience of a single center where all patients received the same solution for organ preservation and were subjected to continuous retrograde blood microcardioplegia during implantation of the graft and to evaluate factors associated to early and late mortality with this technique. This is a retrospective, observational and descriptive study of a single center. During the study period were performed 35 heart transplants. Fifteen (42.9%) patients were in cardiogenic shock. The probability of survival was 74.8±7.8%, 60.4±11.3% and 15.1±13.4% at 1 year, 5 years and 10 years of follow-up, respectively. The median survival time was 96.6 months. The use of myocardial protection with retrograde cardioplegic solution may reduce the risks associated morbidity due to cold ischemia time during the heart transplant, and we suggest that this benefit may be even greater in cases of cold ischemia time longer ensuring protection to the myocardium.
Subject: Adult
Brazil
Cardioplegic Solutions
Epidemiologic Methods
Female
Heart
Heart Arrest, Induced
Heart Transplantation
Humans
Male
Middle Aged
Organ Preservation
Time Factors
Treatment Outcome
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/23288174
Date Issue: -1-Uns- -1
Appears in Collections:Unicamp - Artigos e Outros Documentos

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