Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200218
Type: Artigo de periódico
Title: On The Pathogenesis Of Plasmodium Vivax Malaria: Perspectives From The Brazilian Field.
Author: Costa, Fabio T M
Lopes, Stefanie C P
Albrecht, Letusa
Ataíde, Ricardo
Siqueira, André M
Souza, Rodrigo M
Russell, Bruce
Renia, Laurent
Marinho, Claudio R F
Lacerda, Marcus V G
Abstract: Life-threatening Plasmodium vivax malaria cases, while uncommon, have been reported since the early 20th century. Unfortunately, the pathogenesis of these severe vivax malaria cases is still poorly understood. In Brazil, the proportion of vivax malaria cases has been steadily increasing, as have the number of cases presenting serious clinical complications. The most frequent syndromes associated with severe vivax malaria in Brazil are severe anaemia and acute respiratory distress. Additionally, P. vivax infection may also result in complications associated with pregnancy. Here, we review the latest findings on severe vivax malaria in Brazil. We also discuss how the development of targeted field research infrastructure in Brazil is providing clinical and ex vivo experimental data that benefits local and international efforts to understand the pathogenesis of P. vivax.
Subject: Brazil
Cell Adhesion
Female
Humans
Malaria, Vivax
Plasmodium Vivax
Pregnancy
Pregnancy Complications, Parasitic
Tropical Medicine
Rights: fechado
Identifier DOI: 10.1016/j.ijpara.2012.08.007
Address: http://www.ncbi.nlm.nih.gov/pubmed/23022617
Date Issue: 2012
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

Files in This Item:
File SizeFormat 
pmed_23022617.pdf671.34 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.