Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200132
Type: Artigo de periódico
Title: Mechanical And Biological Performances Of New Scaffolds Made Of Collagen Hydrogels And Fibroin Microfibers For Vascular Tissue Engineering.
Author: de Moraes, Mariana Agostini
Paternotte, Estelle
Mantovani, Diego
Beppu, Marisa Masumi
Abstract: A microstructured composite material made of collagen hydrogel (matrix) and silk fibroin microfibers (randomly oriented reinforcing fibers) is investigated in order to conjugate the mechanical resistance of fibroin with the suitable biological performance of collagen to design new scaffolds for vascular tissue engineering. Results show that fibroin microfibers and collagen fibrils have suitable interfacial adhesion, and the scaffold exhibits improved mechanical properties if compared with a pure collagen hydrogel. Furthermore, the overall biological performance is improved.
Subject: Blood Vessels
Cells, Cultured
Collagen
Fibroins
Humans
Hydrogels
Tensile Strength
Tissue Engineering
Rights: fechado
Identifier DOI: 10.1002/mabi.201200060
Address: http://www.ncbi.nlm.nih.gov/pubmed/22847779
Date Issue: 2012
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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