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|Type:||Artigo de periódico|
|Title:||Hyaluronic Acid Depolymerization By Ascorbate-redox Effects On Solid State Cultivation Of Streptococcus Zooepidemicus In Cashew Apple Fruit Bagasse.|
|Author:||de Macedo, André Casimiro|
Santana, Maria Helena Andrade
|Abstract:||The cashew fruit (Anacardium occidentale L.) has been used as a promising agricultural resource for the production of low-molecular weight (M(W)) hyaluronic acid (HA) (10(4)-10(5) Da). The cashew juice is a rich source of vitamin C containing, 1.2-2.0 g L(-1). This work explores the effects of the initial concentration of the ascorbate on the solid fermentation of the juice-moisturized bagasse from the cashew apple fruit. The results show that the M(W) reduction of HA is proportional to the initial ascorbate concentration. The presence of ascorbate did not influence the Streptococcus zooepidemicus metabolism. However, the HA productivity was increased from 0.18 to 0.28 mg g(-1) h(-1) when the ascorbate concentration ranged from 1.7 to 10 mg mL(-1). These findings contribute to the controlled production of HA in a low M(W) range, which is important in cell signalization, angiogenesis and nanoparticles production.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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