Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200099
Type: Artigo de periódico
Title: Eradication Treatment Of Helicobacter Pylori Infection: Its Importance And Possible Relationship In Preventing The Development Of Gastric Cancer.
Author: Roesler, Bruna Maria
Costa, Sandra Cecília Botelho
Zeitune, José Murilo Robilotta
Abstract: Helicobacter pylori is the most important carcinogen for gastric adenocarcinoma. Bacterial virulence factors are essential players in modulating the immune response involved in the initiation of carcinogenesis in the stomach; host genetic factors contribute to the regulation of the inflammatory response and to the aggravation of mucosal damage. In terms of environmental factors, salt intake and smoking contribute to the development of lesions. Various therapeutic schemes are proposed to eradicate H. pylori infection, which could potentially prevent gastric cancer, offering the greatest benefit if performed before premalignant changes of the gastric mucosa have occurred.
Rights: aberto
Identifier DOI: 10.5402/2012/935410
Address: http://www.ncbi.nlm.nih.gov/pubmed/22778979
Date Issue: 2012
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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