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Type: Artigo de periódico
Title: Primary Synovial Sarcoma Involving The Submandibular Gland.
Author: Mariano, Fernanda Viviane
Oliveira Gondak, Rogério
da Costa, Matheus Vieira
Corrêa, Marcelo Brum
Lopes, Márcio Ajudarte
de Almeida, Oslei Paes
Abstract: Synovial sarcoma represents 5.6%-10% of all soft-tissue sarcomas. Adolescents and young adults are most frequently affected, mainly in the deep soft tissue of the extremities. Only 10% of synovial sarcomas affect the head and neck region; most of these are biphasic. We describe a case of an 18-year-old man who complained of a mass in the right submandibular region that had been present for approximately 12 months. On surgical removal, microscopic analysis showed a tumor formed by sheets of malignant spindle cells involving the submandibular gland. Immunohistochemistry displayed positivity for AE1/AE3, CK18/8, epithelial membrane antigen, CD99, CD56, and TLE-1. Based on these immunohistochemical and histopathologic features, a diagnosis of monophasic synovial sarcoma was rendered. The patient was treated with adjuvant radiotherapy and after 1 year was free of disease. To the best of our knowledge, this is the first reported case of synovial sarcoma involving the submandibular gland.
Subject: Adolescent
Diagnosis, Differential
Sarcoma, Synovial
Submandibular Gland
Submandibular Gland Neoplasms
Tumor Markers, Biological
Citation: Oral Surgery, Oral Medicine, Oral Pathology And Oral Radiology. v. 114, n. 1, p. e61-5, 2012-Jul.
Rights: fechado
Identifier DOI: 10.1016/j.oooo.2011.12.004
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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