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Type: Artigo de periódico
Title: Bariatric Surgery Does Not Interfere With Sperm Quality--a Preliminary Long-term Study.
Author: Reis, Leonardo Oliveira
Zani, Emerson Luis
Saad, Ricardo Destro
Chaim, Elintom Adame
de Oliveira, Laurione Cândido
Fregonesi, Adriano
Abstract: Positive impact of weight loss on sexual function and hormones has been demonstrated, and male fertility in this scenario is to be better defined. We evaluated the impact of lifestyle modifications and gastric bypass on sperm quality. We prospectively studied 20 morbidly obese men during 24 months, randomized for intervention: lifestyle modifications (exercise and diet) for 4 months and subsequently gastric bypass (n = 10); and control: follow-up (n = 10). All patients underwent International Index of Erectile Function (IIEF-5) questionnaire, serum estradiol, prolactin (PRL), luteinizing and follicle-stimulating hormones (LH and FSH), free and total testosterones (FT and TT) and semen analysis at baseline (time 0), surgery 4 months later baseline (time 1) and final evaluation 24 months (time 2). Intervention group presented significant reduction in body mass index (BMI) at times 1 and 2, compared to control. There were no significant differences among sperm parameters between groups at times 0, 1, and 2 and among times 0, 1, and 2 in each group. Increases in IIEF-5 score (P = .0469), TT (P = .0349), and FSH (P = .0025) and reduction in PRL (P < .0001) were observed in the intervention group from times 0 to 2 and 1 to 2. Comparing groups at time 2, IIEF-5, TT, and FT increased significantly in the intervention group (P = .0224, P = .0043, and P = .0149, respectively). Surgery-induced massive weight loss does not interfere with sperm quality, while it increased the quality of sexual function, TT, FT and FSH and reduced PRL. Lifestyle modifications impacted merely the BMI. New studies are warranted, mostly considering birth rate as primary end point and including infertile men.
Subject: Adult
Bariatric Surgery
Body Mass Index
Caloric Restriction
Follicle Stimulating Hormone
Health Surveys
Life Style
Luteinizing Hormone
Middle Aged
Obesity, Morbid
Semen Analysis
Sexual Behavior
Weight Loss
Citation: Reproductive Sciences (thousand Oaks, Calif.). v. 19, n. 10, p. 1057-62, 2012-Oct.
Rights: fechado
Identifier DOI: 10.1177/1933719112440747
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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