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Type: Artigo de periódico
Title: [growth Hormone In Children And Adolescents With Cystic Fibrosis].
Author: Amorim, Pollyana Garcia
Mendes, Thaís de Barros
Oliveira, Lílian Santiago Pinho de
Guerra-Júnior, Gil
Ribeiro, José Dirceu
Abstract: The recombinant human growth hormone (rhGH) can improve weight gain, physical growth, clinical and lung in cystic fibrosis (CF). However, the routine use, although promising, is not established in the literature. The objective of this study was to assess the benefits of rhGH in children and adolescents with CF. We conducted a systematic review in the database PubMed, Lilacs, SciELO and Cochrane, in the period 2000-2010, using the keywords: cystic fibrosis, growth hormone, children and adolescents. We found 77 articles and included 11 randomized controlled trials, with 290 children and adolescents with CF. The short-term use (1-24 months) of rhGH improved the height, weight, growth rate, bone mineral content and components of pulmonary function. Adverse effects, like diabetes, were not observed in the studies. The short-term use of rhGH improved growth and body composition in patients with CF.
Subject: Adolescent
Body Composition
Body Height
Body Weight
Cystic Fibrosis
Growth Hormone
Randomized Controlled Trials As Topic
Weight Gain
Young Adult
Rights: aberto
Identifier DOI: 
Date Issue: 2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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