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Type: Artigo de periódico
Title: Metabolic Evaluation Of Young Women With Congenital Adrenal Hyperplasia.
Author: Schnaider-Rezek, Gabrielle Sormanti
Lemos-Marini, Sofia Helena Valente de
Baptista, Maria Tereza Matias
Guerra-Júnior, Gil
Morcillo, André Moreno
Mello, Maricilda Palandi de
Oliveira, Laurione Cândido de
D'Souza-Li, Lilia
Abstract: To evaluate insulin resistance and lipid profile in women with congenital adrenal hyperplasia (CAH) caused by classical 21-hydroxylase deficiency (21OHD), and their association with body mass index (BMI) and corticosteroid dosage. We assessed BMI, waist circumference, current glucocorticoid dosage, glucose, insulin and lipid profile in eighteen young women (mean ± SD, 19.3 ± 3.0 years) with 21OHD CAH. BMI was normal in 12 patients, 5 of them were overweight, and 1 was obese. Waist circumference was high in 7 patients. Fasting insulin and HOMA-IR were elevated in seven and eight patients, respectively. Total cholesterol and triglycerides were high in only two patients, and HDL-cholesterol was low in four. Insulin resistance was not associated with BMI, waist circumference or glucocorticoid dose. Young women with 21OHD CAH had infrequent dyslipidemia, but had a higher prevalence of insulin resistance and central obesity, that were independent of BMI or corticosteroid dosage.
Subject: Adolescent
Adrenal Hyperplasia, Congenital
Blood Glucose
Body Mass Index
Insulin Resistance
Obesity, Abdominal
Statistics, Nonparametric
Waist Circumference
Young Adult
Rights: aberto
Identifier DOI: 
Date Issue: 2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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