Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/199713
Type: Artigo de periódico
Title: Audiological And Genetics Studies In High-risk Infants.
Author: Colella-Santos, Maria Francisca
Françozo, Maria de Fátima de Campos
do Couto, Christiane Marques
Lima, Maria Cecilia Marconi Pinheiro
Tazinazzio, Tatiana Guilhermino
Castilho, Arthur Menino
Sartorato, Edi Lucia
Abstract: Hearing is one of the main ways with which one person can contact the external world; it plays a key role in their integration with society. The objective of this study was to analyze the results of the hearing, medical and genetic evaluation of high-risk infants who failed the newborn hearing screening. Clinical and experimental study. We assessed thirty-eight neonates, with ages between one and six months. The infants underwent the following procedures: medical interview; immittance testing; Brainstem Auditory Evoked Potential; Transient Evoked Otoacoustic Emission and otorhinolaryngological evaluation. DNA extraction from the oral mucosa was performed for genetic studies using the protocol method adapted from the Human Genetics Lab of the CBMEG/UNICAMP. Regarding gender and presence of risk factors, significant statistically differences were not found in normal hearing infants and in those with hearing loss. Concerning gestational age, term infants were more affected by hearing loss. Hearing loss was identified in 58% of the sample, conduction hearing loss represented 31.5% (12/38) and neurossensory 28.9% of cases. There were none of the genetic mutations most commonly seen in cases with a genetic etiology. Hearing loss was identified in the majority of High-risk infants.
Subject: Audiometry, Evoked Response
Cross-sectional Studies
Evoked Potentials, Auditory, Brain Stem
Female
Gestational Age
Hearing Loss, Conductive
Hearing Loss, Sensorineural
Humans
Infant
Infant, Newborn
Male
Otoacoustic Emissions, Spontaneous
Risk Factors
Severity Of Illness Index
Sex Factors
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/22183286
Date Issue: -1-Uns- -1
Appears in Collections:Unicamp - Artigos e Outros Documentos

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