Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/199585
Type: Artigo de periódico
Title: Heart And Liver T2 Assessment For Iron Overload Using Different Software Programs.
Author: Fernandes, Juliano L
Sampaio, Erika Fontana
Verissimo, Monica
Pereira, Fabricio B
da Silva, Jose Alvaro
de Figueiredo, Gabriel S
Kalaf, Jose M
Coelho, Otavio R
Abstract: To assess the level of agreement and interchangeability among different software programs for calculation of T2 values for iron overload. T2 images were analysed in 60 patients with thalassaemia major using the truncation method in three software programs. Levels of agreement were assessed using Pearson correlation and Bland-Altman plots. Categorical classification for levels of iron concentration by each software program was also compared. For the heart, all correlation coefficients were significant among the software programs (P < 0.001 for all coefficients). The mean differences and 95% limits of agreement were 0.2 (-4.73 to 5.0); 0.1 (-4.0 to 3.9); and -0.1 (-4.3 to 4.8). For the liver all correlations were also significant with P < 0.001. Bland-Altman plots showed differences of -0.02 (-0.7 to 0.6); 0.01 (-0.4 to 0.4); and -0.02 (-0.6 to 0.6). There were no significant differences in clinical classification among the software programs. All tools used in this study provided very good agreement among heart and liver T2 values. The results indicate that interpretation of T2 data is interchangeable with any of the software programs tested. Magnetic resonance imaging in iron overload assessment has become an essential tool. Post processing options to establish T2 values have not been compared. No differences were found on T2 of the liver or heart using 3 different techniques. Availability of these methods should allow more widespread interpretation of iron overload by MRI.
Subject: Adult
Cross-sectional Studies
Female
Humans
Iron
Iron Overload
Liver
Magnetic Resonance Imaging
Male
Myocardium
Software
Beta-thalassemia
Rights: fechado
Identifier DOI: 10.1007/s00330-011-2208-1
Address: http://www.ncbi.nlm.nih.gov/pubmed/21842212
Date Issue: 2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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