Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/199544
Type: Artigo de periódico
Title: Effect Of Mesoporous Silica Under Neisseria Meningitidis Transformation Process: Environmental Effects Under Meningococci Transformation.
Author: Hollanda, Luciana M
Cury, Gisele Cg
Pereira, Rafaella Fc
Ferreira, Gracielle A
Sousa, Andreza
Sousa, Edesia Mb
Lancellotti, Marcelo
Abstract: This study aimed the use of mesoporous silica under the naturally transformable Neisseria meningitidis, an important pathogen implicated in the genetic horizontal transfer of DNA causing a escape of the principal vaccination measures worldwide by the capsular switching process. This study verified the effects of mesoporous silica under N. meningitidis transformation specifically under the capsular replacement. we used three different mesoporous silica particles to verify their action in N. meningitis transformation frequency. we verified the increase in the capsular gene replacement of this bacterium with the three mesoporous silica nanoparticles. the mesouporous silica particles were capable of increasing the capsule replacement frequency in N. meningitidis.
Subject: Bacterial Capsules
Neisseria Meningitidis
Silicon Dioxide
Transformation, Bacterial
Rights: aberto
Identifier DOI: 10.1186/1477-3155-9-28
Address: http://www.ncbi.nlm.nih.gov/pubmed/21787408
Date Issue: 2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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