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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleGrowth Hormone Effect On Body Composition In Turner Syndrome.pt_BR
dc.contributor.authorBaldin, Alexandre Duartept_BR
dc.contributor.authorFabbri, Tatianapt_BR
dc.contributor.authorSiviero-Miachon, Adriana Aparecidapt_BR
dc.contributor.authorSpinola-Castro, Angela Mariapt_BR
dc.contributor.authorde Lemos-Marini, Sofia Helena Valentept_BR
dc.contributor.authorBaptista, Maria Tereza Matiaspt_BR
dc.contributor.authorD'Souza-Li, Lilia Freire Rodriguespt_BR
dc.contributor.authorMaciel-Guerra, Andrea Trevaspt_BR
dc.contributor.authorGuerra-Junior, Gilpt_BR
unicamp.authorAlexandre Duarte Baldin, Pediatric Endocrinology Unit, Department of Pediatrics and Center for Investigation in Pediatrics, Faculty of Medical Sciences (FCM), State University of Campinas (UNICAMP), Campinas, SP, 13083-970, Brazil.pt_BR
unicamp.author.externalTatiana Fabbri,pt
unicamp.author.externalAdriana Aparecida Siviero-Miachon,pt
unicamp.author.externalAngela Maria Spinola-Castro,pt
unicamp.author.externalSofia Helena Valente de Lemos-Marini,pt
unicamp.author.externalMaria Tereza Matias Baptista,pt
unicamp.author.externalLilia Freire Rodrigues D'Souza-Li,pt
unicamp.author.externalAndrea Trevas Maciel-Guerra,pt
unicamp.author.externalGil Guerra-Junior,pt
dc.subjectAdolescentpt_BR
dc.subjectAdultpt_BR
dc.subjectBody Compositionpt_BR
dc.subjectBody Fat Distributionpt_BR
dc.subjectBody Mass Indexpt_BR
dc.subjectCase-control Studiespt_BR
dc.subjectChildpt_BR
dc.subjectCross-sectional Studiespt_BR
dc.subjectFemalept_BR
dc.subjectGrowth Disorderspt_BR
dc.subjectHuman Growth Hormonept_BR
dc.subjectHumanspt_BR
dc.subjectLongitudinal Studiespt_BR
dc.subjectMatched-pair Analysispt_BR
dc.subjectRecombinant Proteinspt_BR
dc.subjectReference Valuespt_BR
dc.subjectTurner Syndromept_BR
dc.subjectYoung Adultpt_BR
dc.description.abstractThis study analyzes the body composition of young adult women with Turner syndrome (TS) either treated or not treated with recombinant human growth hormone (rhGH) and compares them with a group of healthy women. Fifty-two non-treated TS patients (23.0 ± 5.8 years), 30 treated with rhGH (21.5 ± 1.5 years), and 133 healthy young adult women (22.9 ± 3.2 years) were evaluated regarding height (H) and weight, body mass index (BMI), brachial perimeter and tricipital cutaneous fold (fat and lean areas at the arm), sitting height (SRH = sitting height/H × 100), leg length (leg/H), waist and hip circumferences (waist/hip), and bioimpedance (percentages of water, lean mass, and fat mass). Age at start of rhGH therapy varied from 7.8 to 15.1 years (10.0 ± 1.3 years), duration of treatment from 2.8 to 8.2 years (3.7 ± 1.5 years), and the mean dose was 0.42 mg/kg/w (from 0.32 to 0.50 mg/kg/w). Body composition (except height) did not differ between TS groups, but there were differences when compared to the control group: weight and sitting height were lower in TS patients; and BMI, SHR, and leg/H were higher. There was an association between all groups with regards to BMI, waist, SHR, and leg/H, but not in percentage of fat mass. SHR was positively correlated with BMI, waist, hip, and percentage of fat mass. This sample of TS patients (with and without rhGH therapy) did not differ in BMI or body composition. However, there were differences between patients with TS patients and normal healthy women. Regardless of rhGH therapy, TS patients should be monitored, particularly for sitting height, SHR, leg length, leg/H, and waist/hip.en
dc.relation.ispartofEndocrinept_BR
dc.relation.ispartofabbreviationEndocrinept_BR
dc.date.issued2011-Decpt_BR
dc.identifier.citationEndocrine. v. 40, n. 3, p. 486-91, 2011-Dec.pt_BR
dc.language.isoengpt_BR
dc.description.volume40pt_BR
dc.description.firstpage486-91pt_BR
dc.rightsfechadopt_BR
dc.rights.holderpt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1559-0100pt_BR
dc.identifier.doi10.1007/s12020-011-9504-zpt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21720878pt_BR
dc.date.available2015-11-27T13:21:37Z-
dc.date.accessioned2015-11-27T13:21:37Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:21:37Z (GMT). No. of bitstreams: 1 pmed_21720878.pdf: 184720 bytes, checksum: 953b24759c4eda345aabe12e2c3df35f (MD5) Previous issue date: 2011en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199515-
dc.identifier.idPubmed21720878pt_BR
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