Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/199378
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleValue Of Repeat Ultrasound-guided Fine-needle Aspiration In Thyroid Nodule With A First Benign Cytologic Result: Impact Of Ultrasound To Predict Malignancy.pt_BR
dc.contributor.authorMaia, Frederico F Rpt_BR
dc.contributor.authorMatos, Patrícia Spt_BR
dc.contributor.authorPavin, Elizabeth Jpt_BR
dc.contributor.authorVassallo, Josépt_BR
dc.contributor.authorZantut-Wittmann, Denise Ept_BR
unicamp.authorFrederico F R Maia, Division of Endocrinology, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Rua Tessalia Vieira de Camargo, 126-Cidade Universitária 13083-887, Campinas, SP, Brazil. fredfrm@fcm.unicamp.brpt_BR
unicamp.author.externalPatrícia S Matos,pt
unicamp.author.externalElizabeth J Pavin,pt
unicamp.author.externalJosé Vassallo,pt
unicamp.author.externalDenise E Zantut-Wittmann,pt
dc.subjectAdultpt_BR
dc.subjectBiopsy, Fine-needlept_BR
dc.subjectBrazilpt_BR
dc.subjectCalcinosispt_BR
dc.subjectDiagnosis, Differentialpt_BR
dc.subjectFemalept_BR
dc.subjectFollow-up Studiespt_BR
dc.subjectGoiter, Nodularpt_BR
dc.subjectHospitals, Universitypt_BR
dc.subjectHumanspt_BR
dc.subjectMalept_BR
dc.subjectMiddle Agedpt_BR
dc.subjectPrevalencept_BR
dc.subjectReoperationpt_BR
dc.subjectRetrospective Studiespt_BR
dc.subjectThyroid Nodulept_BR
dc.subjectTime Factorspt_BR
dc.subjectTumor Burdenpt_BR
dc.subjectUltrasonography, Interventionalpt_BR
dc.subjectUrban Healthpt_BR
dc.description.abstractThis study aimed to investigate the value of repeat ultrasound-guided fine-needle aspiration (FNAC-US) in benign thyroid nodules and determine the ultrasound (US) predictors of malignancy in this group of nodules. The authors studied 35 of 143 nodules with initially benign cytological result who underwent serial re-biopsy (FNAC-US). By means of surgery, malignancy histology results were confirmed in 10 (28.5%) cases (G1) versus 25 (71.5%) benign nodules (G2). The clinical, lab, scintigraphyc, and US features were compared between the two groups to predict malignancy in thyroid nodules with initially benign cytological result. The cytological finding of 28/35 nodules were change to indeterminate cytology (Bethesda system category III or IV) at second and/or ≥third cytological study. In this group of 28 cases, 23 (82.1%) was identified until the third procedure. The interval between first and third re-biopsy was 13 months (median). There were no differences in age, gender, thyrotropin (TSH) levels, thyroid auto-antibodies, or thyroid dysfunctions. The scintigraphy showed cold nodule in 80% of G1 versus 78.9% of G2 (NS). Sonographic studies showed malignant suspected US features in G1: microcalcifications, central flow, hypoechogenicity, and border irregularity. This study suggests repeating FNAC-US in nodules with first benign cytologic result and suspicious US features of malignancy for at least two times (until the third FNAC) in about 13 months horizon.en
dc.relation.ispartofEndocrinept_BR
dc.relation.ispartofabbreviationEndocrinept_BR
dc.date.issued2011-Octpt_BR
dc.identifier.citationEndocrine. v. 40, n. 2, p. 290-6, 2011-Oct.pt_BR
dc.language.isoengpt_BR
dc.description.volume40pt_BR
dc.description.firstpage290-6pt_BR
dc.rightsfechadopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1559-0100pt_BR
dc.identifier.doi10.1007/s12020-011-9467-0pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21499817pt_BR
dc.date.available2015-11-27T13:21:18Z-
dc.date.accessioned2015-11-27T13:21:18Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:21:18Z (GMT). No. of bitstreams: 1 pmed_21499817.pdf: 1663757 bytes, checksum: b242155c631c29691f5cecd7d85c529b (MD5) Previous issue date: 2011en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199378-
dc.identifier.idPubmed21499817pt_BR
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