Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/199330
Type: Artigo de periódico
Title: Evaluation Of Antifungal Activity Of Medicinal Plant Extracts Against Oral Candida Albicans And Proteinases.
Author: Höfling, José Francisco
Mardegan, Rita Cássia
Anibal, Paula Cristina
Furletti, Vivian Fernandes
Foglio, Mary Ann
Abstract: Proteinases produced by Candida albicans are one kind of virulence factor expressed that contribute to adherence and invasion of host tissue. Proteinase inhibitor of human immunodeficiency virus in experimental candidiasis suggested reduction in fungal infection, and medicinal plants could be a source of alternative agent to prevent diseases. In this study, we investigated the production of proteinases by C. albicans from clinical isolates and the action of plant extracts against strains of C. albicans and its synthesized proteinases, comparing with antifungal fluconazole and amphotericin B and proteinase inhibitors pepstatin A, amprenavir, and ritonavir. The results reported here showed that these extracts have a certain kind of action and that the search for new antifungal agents could be found at the plants.
Subject: Adult
Antifungal Agents
Candida Albicans
Candidiasis, Oral
Child, Preschool
Humans
Microbial Sensitivity Tests
Middle Aged
Peptide Hydrolases
Plant Extracts
Plants, Medicinal
Protease Inhibitors
Rights: fechado
Identifier DOI: 10.1007/s11046-011-9404-z
Address: http://www.ncbi.nlm.nih.gov/pubmed/21409409
Date Issue: 2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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