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Type: Artigo de periódico
Title: Peri-implant Reconstruction Using Autologous Periosteum-derived Cells And Guided Bone Regeneration.
Author: Ribeiro, Fernanda Vieira
Suaid, Fabricia Ferreira
Ruiz, Karina Gonzales Silverio
Rodrigues, Thaisângela Lopes
Carvalho, Marcelo Diniz
Nociti, Francisco Humberto
Sallum, Enilson Antonio
Casati, Márcio Zaffalon
Abstract: This investigation evaluated the bone healing in peri-implant defects treated with periosteum-derived cells (PCs) and guided bone regeneration (GBR). PCs were harvested from six beagle dogs and characterized in vitro with regard to their osteogenic properties. The animals were subjected to teeth extraction in the mandible, and after 3 months of healing, implant sites were drilled, bone dehiscences were created and implants were placed. Dehiscences were randomly assigned to: PCs+GBR, GBR, PCs and non-treated defects. After 3 months, the implants/adjacent tissues were processed. Bone-to-implant contact (BIC) bone fill (BF) within implant threads, and bone area (BA) in a zone lateral to the implant were obtained. In vitro analyses confirmed the osteogenic potential of PCs. Histometrically, no statistically significant differences were observed among the PCs+GBR, GBR and PCs groups for both BF and BIC (p>0.05), whereas these groups showed statistically higher values, as compared with the non-treated group (p<0.05). With respect to BA, the PCs+GBR and GBR groups presented significantly higher means, as compared with the PCs and non-treated groups (p<0.05). Although successful outcomes have been promoted by using the combined approach, PCs in conjunction with membranes did not provide additional benefit during peri-implant bone regeneration, when compared with the therapeutic approaches used alone.
Subject: Alveolar Bone Loss
Alveolar Process
Bone Regeneration
Cell Differentiation
Cell Separation
Dental Implantation, Endosseous
Dental Implants
Guided Tissue Regeneration, Periodontal
Membranes, Artificial
Microscopy, Electron, Scanning
Random Allocation
Tissue Engineering
Tissue Scaffolds
Tissue And Organ Harvesting
Transplantation, Autologous
Treatment Outcome
Citation: Journal Of Clinical Periodontology. v. 37, n. 12, p. 1128-36, 2010-Dec.
Rights: fechado
Identifier DOI: 10.1111/j.1600-051X.2010.01635.x
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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