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Type: Artigo de periódico
Title: Smart Hollow Microspheres Of Chondroitin Sulfate Conjugates And Magnetite Nanoparticles For Magnetic Vector.
Author: Guilherme, Marcos R
Reis, Adriano V
Alves, Bruno R V
Kunita, Marcos H
Rubira, Adley F
Tambourgi, Elias B
Abstract: Smart hollow microspheres composed of vinyled-chondroitin sulfate conjugates (CSπ) and magnetite nanoparticles were obtained by the intermediate of a multiple emulsion in absence of a surfactant, attributable to stabilizing properties of the CS. It was formed an oil-water multiple emulsion in which the CS played a role as an anionic stabilizer for magnetite nanoparticles via complexation. Iron oxides were bonded to the microspheres by the formation of a complex of Fe(3+) ions on the crystalline phase with oxygen atoms at the carboxyl groups without their magnetic properties being affected. The average crystal size of embedded magnetite nanoparticles was approximately 16.5nm, indicative of a good dispersion in microspheres. Furthermore, the introduction of iron oxides resulted in microspheres with a higher diameter and a narrower particle size distribution.
Subject: Chondroitin Sulfates
Ferrosoferric Oxide
Particle Size
Surface Properties
Rights: fechado
Identifier DOI: 10.1016/j.jcis.2010.08.051
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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