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Type: Artigo de periódico
Title: Effect Of Goniothalamin On The Development Of Ehrlich Solid Tumor In Mice.
Author: Vendramini-Costa, Débora Barbosa
de Castro, Ilton Barros Daltro
Ruiz, Ana Lúcia Tasca Góis
Marquissolo, Cilene
Pilli, Ronaldo Aloise
de Carvalho, João Ernesto
Abstract: In this work the antiproliferative activity of goniothalamin (1), both in racemic and in its enantiomeric pure forms, in a solid tumor experimental model using laboratory animals is described. The antiedematogenic activity displayed by racemic 1 in the carrageenan edema model in mice together with the reduction of Ehrlich solid tumor model suggest a relationship between anticancer and antiinflammatory activities with the antiinflammatory activity favoring the antiproliferative activity itself.
Subject: Animals
Anti-inflammatory Agents
Antineoplastic Agents
Carcinoma, Ehrlich Tumor
Cell Line, Tumor
Disease Models, Animal
Citation: Bioorganic & Medicinal Chemistry. v. 18, n. 18, p. 6742-7, 2010-Sep.
Rights: fechado
Identifier DOI: 10.1016/j.bmc.2010.07.053
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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