Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198991
Type: Artigo de periódico
Title: Depressive Symptoms In Rheumatoid Arthritis.
Author: Mella, Lucas Francisco Botequio
Bértolo, Manoel Barros
Dalgalarrondo, Paulo
Abstract: To determine the prevalence of depressive and anxiety symptoms in patients with rheumatoid arthritis (a chronic inflammatory disease) in comparison to a control group with osteoarthritis (a chronic non-inflammatory degenerative disease) and to identify the sociodemographic and clinical variables associated with depressive symptoms in these patients. Sixty-two rheumatoid arthritis patients and 60 osteoarthritis patients participated in the study. Sociodemographic and clinical data were collected and the Hospital Anxiety and Depression Scale and the Disability Index of the Health Assessment Questionnaire were applied. The prevalence of depressive symptoms was of 53.2% in rheumatoid arthritis and 28.3% in osteoarthritis (p = 0.005). The prevalence of anxiety symptoms was of 48.4% in rheumatoid arthritis and 50.0% in osteoarthritis (p = 0.859). The mean (and standard deviation) scores in the Disability Index of the Health Assessment Questionnaire were 1.4 (0.8) in rheumatoid arthritis and 1.4 (0.6) in osteoarthritis (p = 0.864). Rheumatoid arthritis patients with depressive symptoms had lower education and higher disease activity and functional disability. Although these two rheumatic diseases are similar in terms of the pain and functional disability that they cause, a significantly higher prevalence of depressive symptoms was found in rheumatoid arthritis patients. This difference might be explained by the hypothesis of a neuroimmunobiological mechanism related to cytokines in inflammatory diseases, which has been considered as a candidate to the development of depressive symptoms.
Subject: Activities Of Daily Living
Anxiety Disorders
Arthritis, Rheumatoid
Case-control Studies
Chronic Disease
Cross-sectional Studies
Depression
Disability Evaluation
Female
Humans
Male
Middle Aged
Osteoarthritis
Socioeconomic Factors
Citation: Revista Brasileira De Psiquiatria (são Paulo, Brazil : 1999). v. 32, n. 3, p. 257-63, 2010-Sep.
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/20694442
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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