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Type: Artigo de periódico
Title: Low-fluoride Toothpaste And Deciduous Enamel Demineralization Under Biofilm Accumulation And Sucrose Exposure.
Author: Cury, Jaime A
do Amaral, Regiane C
Tenuta, Livia M A
Del Bel Cury, Altair A
Tabchoury, Cínthia P M
Abstract: Because low-fluoride toothpaste (500 p.p.m. F) has not clearly been shown to be effective for controlling caries in caries-active children, this experimental in situ study was conducted to evaluate whether its effect, when compared with a conventional toothpaste (1,000-1,500 p.p.m. F), would depend on the cariogenic challenge. During four phases of 14 d each, 14 volunteers used 500 or 1,100 p.p.m. F toothpaste and wore palatal appliances containing deciduous enamel slabs, on which biofilm was accumulated and exposed to 20% sucrose solution at frequencies increasing from two to eight times per day. The F concentration was determined in the biofilm formed, and enamel demineralization was assessed by surface hardness loss (% SHL) and integrated area of hardness x lesion depth (DeltaS). The F uptake by enamel was also determined. Fluoride in biofilm fluid and solids was statistically higher when conventional F toothpaste was used. The toothpastes did not differ statistically in terms of % SHL, DeltaS, and F in enamel, but only the conventional F toothpaste significantly reduced caries-lesion progression according to the frequency of sucrose exposure. The findings suggest that the high-F availability in biofilm, resulting from the use of conventional toothpaste compared with low-F toothpaste, may be important for reducing caries-lesion progression in conjunction with a high frequency of sucrose exposure.
Subject: Adolescent
Biological Availability
Cariogenic Agents
Cariostatic Agents
Cross-over Studies
Dental Caries
Dental Enamel
Dental Plaque
Dietary Sucrose
Disease Progression
Double-blind Method
Time Factors
Tooth Demineralization
Tooth, Deciduous
Young Adult
Rights: fechado
Identifier DOI: 10.1111/j.1600-0722.2010.00745.x
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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