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Type: Artigo de periódico
Title: Haptoglobin Genotypes In Chagas' Disease.
Author: Jorge, Susan E D C
Abreu, Cristina Feix
Guariento, Maria Elena
Sonati, Maria de Fatima
Abstract: To investigate the existence of an association between haptoglobin (Hp) genotypes and the severity of heart complications in Chagas' disease. Hp genotyping was performed by PCR in 107 Brazilian patients sub-classified in asymptomatic, with mild heart disease and with severe heart disease. Multiple logistic regression (R(2)=24%) indicated that patients with the Hp1-1 genotype have lower probability of developing the severe heart complications. The Hp polymorphism may influence the clinical evolution of Chagas' disease.
Subject: Animals
Chagas Cardiomyopathy
Chagas Disease
Risk Factors
Citation: Clinical Biochemistry. v. 43, n. 3, p. 314-6, 2010-Feb.
Rights: fechado
Identifier DOI: 10.1016/j.clinbiochem.2009.09.020
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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