Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198946
Type: Artigo de periódico
Title: Haptoglobin Genotypes In Chagas' Disease.
Author: Jorge, Susan E D C
Abreu, Cristina Feix
Guariento, Maria Elena
Sonati, Maria de Fatima
Abstract: To investigate the existence of an association between haptoglobin (Hp) genotypes and the severity of heart complications in Chagas' disease. Hp genotyping was performed by PCR in 107 Brazilian patients sub-classified in asymptomatic, with mild heart disease and with severe heart disease. Multiple logistic regression (R(2)=24%) indicated that patients with the Hp1-1 genotype have lower probability of developing the severe heart complications. The Hp polymorphism may influence the clinical evolution of Chagas' disease.
Subject: Animals
Brazil
Chagas Cardiomyopathy
Chagas Disease
Genotype
Haptoglobins
Humans
Risk Factors
Rights: fechado
Identifier DOI: 10.1016/j.clinbiochem.2009.09.020
Address: http://www.ncbi.nlm.nih.gov/pubmed/19804773
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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