Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198910
Type: Artigo de periódico
Title: Systemic Inflammation Caused By Chronic Periodontite In Patients Victims Of Acute Ischemic Heart Attack.
Author: Oliveira, Fernando José de
Vieira, Reinaldo Wilson
Coelho, Otávio Rizzi
Petrucci, Orlando
Oliveira, Pedro Paulo Martins de
Antunes, Nilson
Oliveira, Ivone Pires F de
Antunes, Edson
Abstract: Infectious and inflammatory processes mediated by bacteria in distant sites have been described as a risk factor for acute ischemic heart disease (AIHD). One hundred one patients with AIHD with and without chronic periodontitis (CP) were included in this study. Patients were admitted to the HC UNICAMP and stratified into three groups: in group 1, we selected patients with severe chronic periodontitis (31 men and 19 women, mean age 55.1 +/- 11.29 years old); the group 2 with mild chronic periodontitis (40 men and 28 women, mean age 54.8 +/- 10.37 years old) and group 3 represented by the toothless (43 men and 20 women, mean age 67.5 +/- 8.55 years old). Blood samples were collected to measure the lipid profiles, hematological and blood glucose levels. In addition, biopsies of seventeen coronary arteries with atherosclerosis and an equal number of internal mammary arteries without atherosclerotic degeneration in group 1 were investigated. Statistical analysis by analysis of variance (ANOVA) and Scheffé test for multiple comparisons was performed. Triglyceride and LDL levels were elevated in group 1 than in group 2. HDL were reduced by 20% in group 1 and remained reduced by 8% in toothless. Blood glucose was higher in group 1. DNA of periodontal bacteria was detected in 58.8% of the coronary arteries. Patients with (AIHD) and severe chronic periodontitis may have altered lipid profile, as well as microorganisms associated with CP can permeate into coronary vessels.
Subject: Acute Disease
Aged
Analysis Of Variance
Blood Glucose
Case-control Studies
Chlamydophila Pneumoniae
Chronic Periodontitis
Coronary Vessels
Dna, Bacterial
Female
Humans
Lipids
Male
Mammary Arteries
Middle Aged
Myocardial Ischemia
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/20563468
Date Issue: -1-Uns- -1
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
pmed_20563468por.pdf120.67 kBAdobe PDFView/Open
pmed_20563468eng.pdf120.17 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.