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Type: Artigo de periódico
Title: Proteome Analysis Of Lumbar Spinal Cord From Rats Submitted To Peripheral Lesion During Neonatal Period.
Author: Castro-Dias, Erich
Vieira, André S
Werneck, Claudio C
Langone, Francesco
Novello, José C
Martins-de-Souza, Daniel
Abstract: Every year traumatic peripheral nerve injuries (TPNI) result in considerable physical disability across the world; the mechanisms of plasticity and reorganization of spinal cord circuits following such injuries are complex and not completely understood. A comparative proteome analysis between neonatal rats submitted to peripheral lesion and controls was performed; a number of differentially expressed proteins involved in oxidative stress response, energy metabolism and cytoskeleton rearrangement were revealed, which may support future studies to help in the understanding and a posteriori the treatment of TPNI.
Subject: Animals
Animals, Newborn
Electrophoresis, Gel, Two-dimensional
Lumbar Vertebrae
Peripheral Nervous System Diseases
Rats, Wistar
Spinal Cord
Rights: fechado
Identifier DOI: 10.1007/s00702-010-0403-x
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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