Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198697
Type: Artigo de periódico
Title: Kinetics Of Monofluorophosphate Hydrolysis In A Bacterial Test Plaque In Situ.
Author: Tenuta, L M A
Del Bel Cury, A A
Tabchoury, C P M
Moi, G P
Silva, W J
Cury, J A
Abstract: Models to evaluate the anticaries potential of fluoride (F) formulations containing monofluorophosphate (MFP) should consider the release of F ion to the oral environment by its enzymatic hydrolysis. This was tested in situ, using a test plaque of a strain of Streptococcus mutans which presents high MFPase activity at pH 5.0. The test plaque was exposed to non-F or MFP (1,450 microg F/g) dentifrices and the fluid phase of the plaque was analyzed after 15, 30, 45 and 75 min. MFP concentration in the plaque fluid decreased over time after exposure to MFP dentifrice, but F ion reached 134.9 +/- 32.0 microM at 15 min and decreased significantly only at 75 min, suggesting continuous MFP hydrolysis by the test plaque.
Subject: Adolescent
Adult
Calcium
Cariostatic Agents
Chromogenic Compounds
Cross-over Studies
Dental Plaque
Dentifrices
Double-blind Method
Female
Fluorides
Humans
Hydrogen-ion Concentration
Hydrolysis
Kinetics
Male
Middle Aged
Phosphates
Phosphoric Monoester Hydrolases
Spectrophotometry
Streptococcus Mutans
Time Factors
Young Adult
Rights: fechado
Identifier DOI: 10.1159/000279466
Address: http://www.ncbi.nlm.nih.gov/pubmed/20110697
Date Issue: 2010
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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