Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198697
Type: Artigo
Title: Kinetics of monofluorophosphate hydrolysis in a bacterial test plaque in situ
Author: Tenuta, L.M.A.
Del Bel Cury, A.A.
Tabchoury, C.P.M.
Moi, G.P.
Silva, W.J.
Cury, J.A.
Abstract: Models to evaluate the anticaries potential of fluoride (F) formulations containing monofluorophosphate (MFP) should consider the release of F ion to the oral environment by its enzymatic hydrolysis. This was tested in situ, using a test plaque of a strain of Streptococcus mutans which presents high MFPase activity at pH 5.0. The test plaque was exposed to non-F or MFP (1,450 microg F/g) dentifrices and the fluid phase of the plaque was analyzed after 15, 30, 45 and 75 min. MFP concentration in the plaque fluid decreased over time after exposure to MFP dentifrice, but F ion reached 134.9 +/- 32.0 microM at 15 min and decreased significantly only at 75 min, suggesting continuous MFP hydrolysis by the test plaque.
Models to evaluate the anticaries potential of fluoride (F) formulations containing monofluorophosphate (MFP) should consider the release of F ion to the oral environment by its enzymatic hydrolysis. This was tested in situ, using a test plaque of a strain of Streptococcus mutans which presents high MFPase activity at pH 5.0. The test plaque was exposed to non-F or MFP (1,450 µg F/g) dentifrices and the fluid phase of the plaque was analyzed after 15, 30, 45 and 75 min. MFP concentration in the plaque fluid decreased over time after exposure to MFP dentifrice, but F ion reached 134.9 ± 32.0 µM at 15 min and decreased significantly only at 75 min, suggesting continuous MFP hydrolysis by the test plaque
Subject: Dentifrícios
Fluoretos
Placas dentárias
Fosfatases
Country: Suiça
Editor: Karger
Citation: Caries Research. v. 44, n. 1, p. 55-9, 2010.
Rights: fechado
Identifier DOI: 10.1159/000279466
Address: https://www.karger.com/Article/Abstract/279466
Date Issue: 2010
Appears in Collections:FOP - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
20110697.pdf579.3 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.