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Type: Artigo de periódico
Title: Variations In Body Mass Index Of Users Of Depot-medroxyprogesterone Acetate As A Contraceptive.
Author: Pantoja, Márcia
Medeiros, Tatiane
Baccarin, Maria Carolina
Morais, Sirlei Siani
Bahamondes, Luis
Fernandes, Arlete Maria dos Santos
Abstract: Weight gain is a frequent reason for discontinuing the contraceptive with depot-medroxyprogesterone acetate (DMPA). This 3-year retrospective cohort study assessed body mass index (BMI; kg/m(2)) variations in 379 current or past DMPA users compared to TCu380A intrauterine device (IUD) users matched for age and BMI, categorized into G1 (normal weight), G2 (overweight) or G3 (obese) according to baseline BMI. Variations in weight and BMI were evaluated using analysis of variance. BMI increased progressively in all groups but significantly more in G1 and G2 DMPA users compared to nonusers and according to duration of use. In the G3 subgroup, weight trends were similar in the DMPA and IUD users. Normal and overweight women increased BMI with DMPA use; however, obese women did not increase weight. Weight increase in DMPA users could be associated with metabolic alterations related to duration of use in normal and overweight women and to alterations already present in obese women. Prospective studies are required to determine triggering factors. DMPA use <or=3 years was not associated with weight increase in women with BMI (kg/m(2)) >or=30.
Subject: Adult
Analysis Of Variance
Body Mass Index
Body Weight
Cohort Studies
Contraceptive Agents, Female
Intrauterine Devices, Copper
Medroxyprogesterone Acetate
Retrospective Studies
Weight Gain
Citation: Contraception. v. 81, n. 2, p. 107-11, 2010-Feb.
Rights: fechado
Identifier DOI: 10.1016/j.contraception.2009.07.008
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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