Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198641
Type: Artigo de periódico
Title: Study Of Kinetic Parameters In A Mechanistic Model For Bioethanol Production Through A Screening Technique And Optimization.
Author: de Andrade, Rafael Ramos
Rivera, Elmer Ccopa
Atala, Daniel I P
Filho, Rubens Maciel
Filho, Francisco Maugeri
Costa, Aline C
Abstract: The accurate description of the kinetics and robust modeling of biotechnological processes can only be achieved by incorporating reliable methodologies to easily update the model when there are changes in operational conditions. The purpose of this work is to provide a systematic approach with which to perform model parameters screening and updating in biotechnological processes. Batch experiments are performed to develop a mechanistic model, considering the effect of temperature on the kinetics, and further experiments (batch fermentations using sugar cane molasses from a different harvest) are used to validate the effectiveness of screening before parameters updating. The reduction in the number of kinetic parameters to be re-estimated enabled by the screening procedure reduces significantly the complexity of the optimization, which makes the updating procedure to be significantly quicker, while resulting in accurate performance of the updated model.
Subject: Carbohydrate Metabolism
Cell Proliferation
Computer Simulation
Ethanol
Kinetics
Models, Biological
Quality Control
Saccharomyces Cerevisiae
Rights: fechado
Identifier DOI: 10.1007/s00449-008-0291-8
Address: http://www.ncbi.nlm.nih.gov/pubmed/19125302
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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