Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198530
Type: Artigo de periódico
Title: Subgemmal Neurogenous Plaque: Clinical And Microscopic Evaluation Of 7 Cases.
Author: Gueiros, Luiz Alcino
León, Jorge Esquiche
Leão, Jair Carneiro
Lopes, Márcio Ajudarte
Jorge, Jacks
de Almeida, Oslei Paes
Abstract: Subgemmal neurogenous plaques (SNPs) are biphasic neural structures found on the posterolateral border of the tongue. Fewer than 40 cases have been reported and only a few were symptomatic. The present report details the features of 7 cases of SNP retrieved from the files of a single institution. Clinical and histopathological data were reviewed and immunohistochemical analysis was performed for S100, CD56, neuron-specific enolase, epithelial membrane antigen, CK7, CK8, CK14, and CK20. All cases showed similar morphological and immunohistochemical characteristics. Neural markers highlighted the biphasic pattern and CK7, CK8, and CK20 were detected on taste buds confined to the epithelium adjacent to the SNPs. Five patients presented pain/discomfort as the main symptom. Symptomatic SNPs seems to be more common than previously reported, presenting as focal burning on the posterolateral border of the tongue.
Subject: Adult
Burning Mouth Syndrome
Female
Humans
Immunohistochemistry
Lymphoid Tissue
Male
Middle Aged
Nerve Net
Neuroma
Plaque, Amyloid
Taste Buds
Tongue
Tongue Neoplasms
Rights: fechado
Identifier DOI: 10.1016/j.tripleo.2009.07.038
Address: http://www.ncbi.nlm.nih.gov/pubmed/19913727
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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