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Type: Artigo de periódico
Title: Comparison Of 2.5% Sodium Hypochlorite And 2% Chlorhexidine Gel On Oral Bacterial Lipopolysaccharide Reduction From Primarily Infected Root Canals.
Author: Gomes, Brenda P F A
Martinho, Frederico C
Vianna, Morgana E
Abstract: This clinical study was conducted to compare the efficacy of chemomechanical preparation with 2.5% sodium hypochlorite (NaOCl) and 2% chlorhexidine (CHX) gel on eliminating oral bacterial lipopolysaccharide (LPS) in teeth with pulp necrosis and apical periodontitis. Fifty-four root canals were selected. Samples were collect before (s1) and after chemomechanical preparation (s2). Teeth were randomly divided into groups: GI, 2.5% NaOCl (n = 27) and GII, CHX gel (n = 27). Limulus amebocyte lysate assay was used to quantify endotoxins. Endotoxin was present in 100% of the samples investigated, with a median value of 272 endotoxin units (EU)/mL (GI) and of 152.46 EU/mL (GII). As a result of chemomechanical preparation, LPS content was reduced to a median value of 86 EU/mL (GI) and 85 EU/mL (GII). Higher percentage value of endotoxin reduction was found in GI (P < .05). The 2.5% NaOCl and 2% CHX gel were not effective in eliminating endotoxin from the primarily infected root canals.
Subject: Adolescent
Anti-infective Agents, Local
Chromogenic Compounds
Dental Pulp Cavity
Dental Pulp Necrosis
Middle Aged
Periapical Periodontitis
Root Canal Irrigants
Root Canal Preparation
Sodium Hypochlorite
Treatment Outcome
Young Adult
Rights: fechado
Identifier DOI: 10.1016/j.joen.2009.06.011
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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