Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198487
Type: Artigo de periódico
Title: Comparison Of 2.5% Sodium Hypochlorite And 2% Chlorhexidine Gel On Oral Bacterial Lipopolysaccharide Reduction From Primarily Infected Root Canals.
Author: Gomes, Brenda P F A
Martinho, Frederico C
Vianna, Morgana E
Abstract: This clinical study was conducted to compare the efficacy of chemomechanical preparation with 2.5% sodium hypochlorite (NaOCl) and 2% chlorhexidine (CHX) gel on eliminating oral bacterial lipopolysaccharide (LPS) in teeth with pulp necrosis and apical periodontitis. Fifty-four root canals were selected. Samples were collect before (s1) and after chemomechanical preparation (s2). Teeth were randomly divided into groups: GI, 2.5% NaOCl (n = 27) and GII, CHX gel (n = 27). Limulus amebocyte lysate assay was used to quantify endotoxins. Endotoxin was present in 100% of the samples investigated, with a median value of 272 endotoxin units (EU)/mL (GI) and of 152.46 EU/mL (GII). As a result of chemomechanical preparation, LPS content was reduced to a median value of 86 EU/mL (GI) and 85 EU/mL (GII). Higher percentage value of endotoxin reduction was found in GI (P < .05). The 2.5% NaOCl and 2% CHX gel were not effective in eliminating endotoxin from the primarily infected root canals.
Subject: Adolescent
Adult
Anti-infective Agents, Local
Chlorhexidine
Chromogenic Compounds
Dental Pulp Cavity
Dental Pulp Necrosis
Endotoxins
Humans
Lipopolysaccharides
Middle Aged
Periapical Periodontitis
Root Canal Irrigants
Root Canal Preparation
Sodium Hypochlorite
Treatment Outcome
Young Adult
Rights: fechado
Identifier DOI: 10.1016/j.joen.2009.06.011
Address: http://www.ncbi.nlm.nih.gov/pubmed/19801228
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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