Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198485
Type: Artigo de periódico
Title: Bioactivity Of Flavonoids Isolated From Lychnophora Markgravii Against Leishmania Amazonensis Amastigotes.
Author: Salvador, Marcos José
Sartori, Fabiana Terezinha
Sacilotto, Ana Claudia B C
Pral, Elizabeth M F
Alfieri, Silvia Celina
Vichnewski, Walter
Abstract: The bioactivity of the flavonoids pinostrobin (1), pinocembrin (2), tectochrysin (3), galangin 3-methyl ether (4), and tiliroside (5) isolated from Lychnophora markgravii aerial parts was investigated in vitro against amastigote stages of Leishmania amazonensis. The compounds were isolated by several chromatographic techniques and their chemical structures were established by ESI-MS and NMR spectroscopic data. The flavonoids 1 and 3 were the most active compounds; they markedly reduced the viability of Leishmania amastigotes.
Subject: Amphotericin B
Animals
Antiprotozoal Agents
Asteraceae
Flavanones
Flavonoids
Leishmania
Models, Molecular
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/19791501
Date Issue: -1-Uns- -1
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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