Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198305
Type: Artigo de periódico
Title: Alveolar Dead Space And Capnographic Variables Before And After Thrombolysis In Patients With Acute Pulmonary Embolism.
Author: Moreira, Marcos Mello
Terzi, Renato G G
Carvalho, Carlos Heitor N
de Oliveira Neto, Antonio Francisco
Pereira, Mônica Corso
Paschoal, Ilma Aparecida
Abstract: Pulmonary embolism (PE) is a common condition. The central aim of this study was to describe the use of volumetric capnography (VCap) before and after fibrinolytic treatment of major PE. Lung scintigraphy was used as a base of comparison for the results of this treatment. We describe the cases of two conscious and spontaneously breathing patients (20- and by 24-year-old women) with major PE undergoing thrombolysis. Curves of CO(2) were obtained VCap and associated with arterial blood gas analysis and D-dimer. The pattern of VCap was compared with the VCap of health volunteers. Parameters also calculated were: P(a-et)CO(2) gradient, alveolar dead space fraction (AVDSf ), late dead space fraction (fDlate), and slope phase III (Slp III). The VCap results before and after thrombolysis for patients 1 and 2 were, respectively, P(a-et)CO(2): 12.6 to 5.8 and 7.9 to 1.6 (mmHg); AVDSf: 0.46 to 0.18 and 0.25 to 0.05; fDlate: 0.46 to 0.21 and 0.24 to 0.04; Slp III: 1.75 to 5.10 and 1.21 to 5.61 (mmHg/L). Lung scintigraphy was used to compare VCap results from the two subjects with VCap results from healthy volunteers and pigs before and after treatment associated with arterial blood gas, D-dimer, and showed satisfactory agreement.
Subject: Acute Disease
Animals
Biological Markers
Capnography
Carbon Dioxide
Female
Fibrin Fibrinogen Degradation Products
Humans
Models, Biological
Perfusion Imaging
Pulmonary Circulation
Pulmonary Embolism
Respiratory Dead Space
Swine
Thrombolytic Therapy
Treatment Outcome
Ventilation-perfusion Ratio
Young Adult
Capnography
Fibrin Fibrinogen Degradation Products/fibrin Fragment D
Pulmonary Embolism
Respiratory Dead Space
Thrombolysis
Citation: Vascular Health And Risk Management. v. 5, n. 1, p. 9-12, 2009.
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/19436653
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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