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Type: Artigo de periódico
Title: Alveolar Dead Space And Capnographic Variables Before And After Thrombolysis In Patients With Acute Pulmonary Embolism.
Author: Moreira, Marcos Mello
Terzi, Renato G G
Carvalho, Carlos Heitor N
de Oliveira Neto, Antonio Francisco
Pereira, Mônica Corso
Paschoal, Ilma Aparecida
Abstract: Pulmonary embolism (PE) is a common condition. The central aim of this study was to describe the use of volumetric capnography (VCap) before and after fibrinolytic treatment of major PE. Lung scintigraphy was used as a base of comparison for the results of this treatment. We describe the cases of two conscious and spontaneously breathing patients (20- and by 24-year-old women) with major PE undergoing thrombolysis. Curves of CO(2) were obtained VCap and associated with arterial blood gas analysis and D-dimer. The pattern of VCap was compared with the VCap of health volunteers. Parameters also calculated were: P(a-et)CO(2) gradient, alveolar dead space fraction (AVDSf ), late dead space fraction (fDlate), and slope phase III (Slp III). The VCap results before and after thrombolysis for patients 1 and 2 were, respectively, P(a-et)CO(2): 12.6 to 5.8 and 7.9 to 1.6 (mmHg); AVDSf: 0.46 to 0.18 and 0.25 to 0.05; fDlate: 0.46 to 0.21 and 0.24 to 0.04; Slp III: 1.75 to 5.10 and 1.21 to 5.61 (mmHg/L). Lung scintigraphy was used to compare VCap results from the two subjects with VCap results from healthy volunteers and pigs before and after treatment associated with arterial blood gas, D-dimer, and showed satisfactory agreement.
Subject: Acute Disease
Biological Markers
Carbon Dioxide
Fibrin Fibrinogen Degradation Products
Models, Biological
Perfusion Imaging
Pulmonary Circulation
Pulmonary Embolism
Respiratory Dead Space
Thrombolytic Therapy
Treatment Outcome
Ventilation-perfusion Ratio
Young Adult
Fibrin Fibrinogen Degradation Products/fibrin Fragment D
Pulmonary Embolism
Respiratory Dead Space
Citation: Vascular Health And Risk Management. v. 5, n. 1, p. 9-12, 2009.
Rights: aberto
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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