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| Type: | Artigo de periódico |
| Title: | Treatment With An Anti-inflammatory Drug Is Detrimental For Muscle Regeneration At Bothrops Jararacussu Envenoming: An Experimental Study. |
| Author: | Vomero, Viviane Urbini Marques, Maria Julia Neto, Humberto Santo |
| Abstract: | We evaluated the effects of deflazacort (DFZ) on muscle regeneration following Bothrops jararacussu envenoming. Tibialis anterior muscle from adult mice was injected with 80 microg of venom. Animals received DFZ during 6days. Seven and 60 days after envenoming, DFZ lead to a decrease in the total number of muscle fibers and an increase in interstitial fibrosis. We conclude that DFZ treatment may aggravate the loss of muscle mass after B. jararacussu envenoming. |
| Subject: | Animals Anti-inflammatory Agents Bothrops Crotalid Venoms Male Mice Muscle, Skeletal Pregnenediones Regeneration Snake Bites |
| Citation: | Toxicon : Official Journal Of The International Society On Toxinology. v. 54, n. 3, p. 361-3, 2009-Sep. |
| Rights: | fechado |
| Identifier DOI: | 10.1016/j.toxicon.2009.04.006 |
| Address: | http://www.ncbi.nlm.nih.gov/pubmed/19375446 |
| Date Issue: | 2009 |
| Appears in Collections: | Unicamp - Artigos e Outros Documentos |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| pmed_19375446.pdf | 1.14 MB | Adobe PDF | View/Open |
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