Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/198268
Type: Artigo de periódico
Title: Treatment With An Anti-inflammatory Drug Is Detrimental For Muscle Regeneration At Bothrops Jararacussu Envenoming: An Experimental Study.
Author: Vomero, Viviane Urbini
Marques, Maria Julia
Neto, Humberto Santo
Abstract: We evaluated the effects of deflazacort (DFZ) on muscle regeneration following Bothrops jararacussu envenoming. Tibialis anterior muscle from adult mice was injected with 80 microg of venom. Animals received DFZ during 6days. Seven and 60 days after envenoming, DFZ lead to a decrease in the total number of muscle fibers and an increase in interstitial fibrosis. We conclude that DFZ treatment may aggravate the loss of muscle mass after B. jararacussu envenoming.
Subject: Animals
Anti-inflammatory Agents
Bothrops
Crotalid Venoms
Male
Mice
Muscle, Skeletal
Pregnenediones
Regeneration
Snake Bites
Citation: Toxicon : Official Journal Of The International Society On Toxinology. v. 54, n. 3, p. 361-3, 2009-Sep.
Rights: fechado
Identifier DOI: 10.1016/j.toxicon.2009.04.006
Address: http://www.ncbi.nlm.nih.gov/pubmed/19375446
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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