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http://repositorio.unicamp.br/jspui/handle/REPOSIP/198176
Type: | Artigo de periódico |
Title: | A New Generation Of More Ph Stable Reversed Phases Prepared By Silanization Of Zirconized Silica. |
Author: | Silva, César R Airoldi, Claudio Collins, Kenneth E Collins, Carol H |
Abstract: | To further extend our studies in the search for reversed phases with enhanced durability at high pH, zirconized silica has now been explored as an alternative support. The synthesis of the new stationary phases involves silanization of a zirconium-modified silica support with a C(18) trifunctional silane, followed by endcapping. The chromatographic properties of the C(18) phases based on zirconized silica are similar to their titanized silica counterparts. Accelerated high pH stability tests, using phosphate mobile phases and elevated temperature, have shown that the zirconized silica phases have promising advantages not only over similarly prepared non-metalized phases but also over titanized silica C(18) phases. |
Subject: | Chemistry, Physical Chromatography, High Pressure Liquid Drug Stability Hydrogen-ion Concentration Magnetic Resonance Spectroscopy Physicochemical Phenomena Silanes Silicon Dioxide Spectrometry, X-ray Emission Spectrophotometry, Infrared Zirconium |
Citation: | Journal Of Chromatography. A. v. 1191, n. 1-2, p. 90-8, 2008-May. |
Rights: | fechado |
Identifier DOI: | 10.1016/j.chroma.2008.01.017 |
Address: | http://www.ncbi.nlm.nih.gov/pubmed/18243228 |
Date Issue: | 2008 |
Appears in Collections: | Unicamp - Artigos e Outros Documentos |
Files in This Item:
File | Size | Format | |
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pmed_18243228.pdf | 671.83 kB | Adobe PDF | View/Open |
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