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Type: Artigo de periódico
Title: Fluoride Release From Caf2 And Enamel Demineralization.
Author: Tenuta, L M A
Cerezetti, R V
Del Bel Cury, A A
Tabchoury, C P M
Cury, J A
Abstract: The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF(2)) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF(2) formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase of F availability in fluid of subsequently formed plaque. We created distinct levels of CaF(2) on enamel to evaluate a dose-response effect. Enamel blocks were mounted in contact with a S. mutans test plaque and used in situ by 10 volunteers. F released to the fluid phase of this substrate (plaque fluid) was measured before a cariogenic challenge. Plaque fluid F concentration was highly correlated to the enamel CaF(2) concentration (r = 0.96, p < 0.001) and to consequent enamel demineralization (r = -0.75, p < 0.001). The results suggest that F released to plaque fluid from CaF(2) formed on enamel may play a significant role in the anticaries effect of professionally applied F agents.
Subject: Acidulated Phosphate Fluoride
Biological Availability
Calcium Fluoride
Cariostatic Agents
Cross-over Studies
Dental Enamel
Dental Plaque
Dose-response Relationship, Drug
Double-blind Method
Fluorides, Topical
Tooth Demineralization
Rights: fechado
Identifier DOI: 
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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