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Type: | Artigo |
Title: | Fluoride release from Caf2 and enamel demineralization |
Author: | Tenuta, L.M.A. Cerezetti, R.V. Del Bel Cury, A.A. Tabchoury, C.P.M. Cury, J.A. |
Abstract: | The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF(2)) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF(2) formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase of F availability in fluid of subsequently formed plaque. We created distinct levels of CaF(2) on enamel to evaluate a dose-response effect. Enamel blocks were mounted in contact with a S. mutans test plaque and used in situ by 10 volunteers. F released to the fluid phase of this substrate (plaque fluid) was measured before a cariogenic challenge. Plaque fluid F concentration was highly correlated to the enamel CaF(2) concentration (r = 0.96, p < 0.001) and to consequent enamel demineralization (r = -0.75, p < 0.001). The results suggest that F released to plaque fluid from CaF(2) formed on enamel may play a significant role in the anticaries effect of professionally applied F agents. The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF2) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF2 formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase of F availability in fluid of subsequently formed plaque. We created distinct levels of CaF2 on enamel to evaluate a dose-response effect. Enamel blocks were mounted in contact with a S. mutans test plaque and used in situ by 10 volunteers. F released to the fluid phase of this substrate (“plaque fluid”) was measured before a cariogenic challenge. “Plaque fluid” F concentration was highly correlated to the enamel CaF2 concentration (r = 0.96, p < 0.001) and to consequent enamel demineralization (r = −0.75, p < 0.001). The results suggest that F released to plaque fluid from CaF2 formed on enamel may play a significant role in the anticaries effect of professionally applied F agents |
Subject: | Fluoretos Desmineralização Fluoreto de cálcio |
Country: | Estados Unidos |
Editor: | Sage |
Citation: | Journal Of Dental Research. v. 87, n. 11, p. 1032-6, 2008-Nov. |
Rights: | fechado |
Identifier DOI: | 10.1177/154405910808701105 |
Address: | https://journals.sagepub.com/doi/10.1177/154405910808701105 |
Date Issue: | 2008 |
Appears in Collections: | FOP - Artigos e Outros Documentos |
Files in This Item:
File | Size | Format | |
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18946010.pdf | 660.21 kB | Adobe PDF | View/Open |
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