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Type: Artigo de periódico
Title: [short Stature In Chronic Kidney Disease: Physiopathology And Treatment With Growth Hormone].
Author: Oliveira, Josenilson Campos de
Siviero-Miachon, Adriana A
Spinola-Castro, Angela Maria
Belangero, Vera Maria Santoro
Guerra-Junior, Gil
Abstract: Growth failure is frequent and a clinically important issue in children with chronic kidney disease (CKD). Many factors contribute to impaired growth in these children, including abnormalities in the growth hormone (GH)--insulin-like growth factor 1 (IGF-1) axis, malnutrition, acidosis, renal bone disease and glucocorticoid associated treatment. The management of growth failure in children with CKD is complicated by the presence of other-disease related complications requiring medical intervention. Despite evidence of GH efficacy and safety in this population, this therapy is still underutilized. This review shows the impact, the causes and the treatment of growth failure in children with CKD.
Subject: Adrenal Cortex Hormones
Body Height
Growth Disorders
Human Growth Hormone
Insulin-like Growth Factor I
Kidney Failure, Chronic
Rights: aberto
Identifier DOI: 
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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