Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197973
Type: Artigo de periódico
Title: Systemic Envenomation Caused By The Wandering Spider Phoneutria Nigriventer, With Quantification Of Circulating Venom.
Author: Bucaretchi, Fábio
Mello, Sueli Moreira
Vieira, Ronan José
Mamoni, Ronei Luciano
Blotta, Maria Heloísa Souza Lima
Antunes, Edson
Hyslop, Stephen
Abstract: Bites by Phoneutria spp. spiders are common in Brazil, although only 0.5-1% result in severe envenomation, with most of these occurring in children. Cases of systemic envenomation in adults are very unusual, and no serum venom levels have been previously quantified in these cases. A 52-year-old man was bitten on the neck by an adult female Phoneutria nigriventer. Immediately after the bite, there was intense local pain followed by blurred vision, profuse sweating, tremors, and an episode of vomiting; 1-2 h post bite the patient showed agitation and a blood pressure of 200/130 mmHg, and was given captopril and meperidine. Upon admission to our service 4 h post bite (time zero - T0), his blood pressure was 130/80 mmHg with a heart rate of 150 beats/min, mild tachypnea, agitation, cold extremities, profuse sweating, generalized tremors, and priapism. The patient was treated with antivenom, local anesthetic, and fluid replacement. Most of the systemic manifestations disappeared within 1 h after antivenom. Laboratory blood analyses at T0, T1, T6, T24, and T48 detected circulating venom by ELISA only at T0, before antivenom infusion (47.5 ng/mL; cut-off, 17.1 ng/mL); his serum blood sugar was 163 mg/dL at T0. The patient was discharged on the second day with a normal arterial blood pressure and a follow-up evaluation revealed no sequelae. This is the first report of confirmed moderate/severe envenoming in an adult caused by P. nigriventer with the quantification of circulating venom.
Subject: Anesthetics, Local
Animals
Antivenins
Brazil
Captopril
Enzyme-linked Immunosorbent Assay
Female
Follow-up Studies
Humans
Hypertension
Male
Meperidine
Middle Aged
Spider Bites
Spider Venoms
Spiders
Time Factors
Rights: fechado
Identifier DOI: 10.1080/15563650802258524
Address: http://www.ncbi.nlm.nih.gov/pubmed/18788004
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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