Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197956
Type: Artigo de periódico
Title: Electrocatalysis Of Reduced L-glutathione Oxidation By Iron(iii) Tetra-(n-methyl-4-pyridyl)-porphyrin (fet4mpyp) Adsorbed On Multi-walled Carbon Nanotubes.
Author: Luz, Rita C S
Damos, Flavio S
Tanaka, Auro A
Kubota, Lauro T
Gushikem, Yoshitaka
Abstract: The development of a highly sensitive voltammetric sensor for reduced l-glutathione (GSH) using a basal plane pyrolytic graphite (BPPG) electrode modified with iron(III) tetra-(N-methyl-4-pyridyl)-porphyrin (FeT4MPyP) adsorbed on multi-walled carbon nanotubes (MWCNT) is described. Scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS) were used to verify the morphologies and composition of the MWCNT after modification with the FeT4MPyP complex. The modified electrode showed very efficient electrocatalytic activity for l-glutathione oxidation, substantially decreasing the oxidation peak to -0.025V vs Ag/AgCl. A linear response range from 5 micromolL(-1) to 5 mmolL(-1) was obtained with a sensitivity of 703.41 microALmmol(-1). The detection limit for GSH determination was 0.5 micromolL(-1) and the relative standard deviation (R.S.D.) for 10 determinations of 250 micromolL(-1) GSH was 1.4%. The modified electrode was applied for GSH determination in erythrocyte samples and the results were in agreement to those obtained by a comparative method described in the literature.
Subject: Adsorption
Artifacts
Buffers
Carbon
Catalysis
Electrochemistry
Electrodes
Glutathione
Hydrogen-ion Concentration
Kinetics
Metalloporphyrins
Nanocomposites
Nanotubes, Carbon
Oxidation-reduction
Rotation
Surface Properties
Rights: fechado
Identifier DOI: 10.1016/j.talanta.2008.05.009
Address: http://www.ncbi.nlm.nih.gov/pubmed/18761161
Date Issue: 2008
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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