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Type: Artigo de periódico
Title: Blends Of Poly(3-hydroxybutyrate) And Poly(p-dioxanone): Miscibility, Thermal Stability And Biocompatibility.
Author: Dias, Michelle
Antunes, M Cecilia Moraes
Santos, Arnaldo R
Felisberti, M Isabel
Abstract: The miscibility, the thermal degradation and biocompatibility of the blends of two biodegradable and bioreabsorbable polymers, brittle polyhydroxybutyric acid (PHB) and flexible poly (p-dioxanone) (PPD) are reported. The blends were prepared by casting from chloroform solutions and analyzed by differential scanning calorimetry, dynamic mechanical analysis, scanning electron microscopy and thermal gravimetric analysis. The blends are immiscible and present promising morphology of a dense phase and a microporous phase, one or the other being the matrix, depending on the composition. Despite the immiscibility, the thermal stability under an inert atmosphere is improved for both polymers. The results obtained from toxicity tests showed that PHB/PPD blends do not present indirect or direct cytotoxicity as a substrate for cellular growth.
Subject: Animals
Biocompatible Materials
Calorimetry, Differential Scanning
Cercopithecus Aethiops
Microscopy, Electron, Scanning
Molecular Structure
Vero Cells
Citation: Journal Of Materials Science. Materials In Medicine. v. 19, n. 12, p. 3535-44, 2008-Dec.
Rights: fechado
Identifier DOI: 10.1007/s10856-008-3531-1
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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