Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: The Role Of High-risk Hpv-dna Testing In The Male Sexual Partners Of Women With Hpv-induced Lesions.
Author: Giraldo, Paulo C
Eleutério, Jose
Cavalcante, Diane Isabelle M
Gonçalves, Ana Katherine S
Romão, Juliana A A
Eleutério, Renata M N
Abstract: The objectives were to assess the prevalence of high-risk HPV in the male sexual partners of women with HPV-induced lesions, and correlate it with biopsies guided by peniscopy. Fifty-four asymptomatic male sexual partners of women with low-grade squamous intra-epithelial lesions (LSIL) associated with high-risk HPV were examined between April 2003 and June 2005. The DNA-HPV was tested using a second-generation hybrid capture technique in scraped penile samples. Peniscopy identified acetowhite lesions leading to biopsy. High-risk HPV was present in 25.9% (14 out of 54) of the cases. Peniscopy led to 13 biopsies (24.07%), which resulted in two cases of condyloma, two cases of intra-epithelial neoplasia (PIN) I, one case of PIN II, and eight cases of normal tissue. The high-risk HPV test demonstrated 80% sensitivity, 100% specificity, 100% positive predictive value, and 88.9% negative predictive value for the identification of penile lesions. There was a greater chance of finding HPV lesions in the biopsy in the positive cases of high-risk HPV with abnormal peniscopy (p=0.007); OR=51 (CI 1.7-1527.1). Among asymptomatic male sexual partners of women with low-grade intra-epithelial squamous lesions, those infected by high-risk HPV have a higher chance of having abnormal penile tissue compared with male partners without that infection.
Subject: Adolescent
Carcinoma In Situ
Cross-sectional Studies
Dna, Viral
Diagnostic Tests, Routine
Human Papillomavirus 16
Human Papillomavirus 18
Middle Aged
Papillomavirus Infections
Penile Diseases
Penile Neoplasms
Sensitivity And Specificity
Sexual Partners
Uterine Cervical Neoplasms
Citation: European Journal Of Obstetrics, Gynecology, And Reproductive Biology. v. 137, n. 1, p. 88-91, 2008-Mar.
Rights: fechado
Identifier DOI: 10.1016/j.ejogrb.2006.12.026
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_17485158.pdf109.93 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.