Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197665
Type: Artigo de periódico
Title: The Role Of High-risk Hpv-dna Testing In The Male Sexual Partners Of Women With Hpv-induced Lesions.
Author: Giraldo, Paulo C
Eleutério, Jose
Cavalcante, Diane Isabelle M
Gonçalves, Ana Katherine S
Romão, Juliana A A
Eleutério, Renata M N
Abstract: The objectives were to assess the prevalence of high-risk HPV in the male sexual partners of women with HPV-induced lesions, and correlate it with biopsies guided by peniscopy. Fifty-four asymptomatic male sexual partners of women with low-grade squamous intra-epithelial lesions (LSIL) associated with high-risk HPV were examined between April 2003 and June 2005. The DNA-HPV was tested using a second-generation hybrid capture technique in scraped penile samples. Peniscopy identified acetowhite lesions leading to biopsy. High-risk HPV was present in 25.9% (14 out of 54) of the cases. Peniscopy led to 13 biopsies (24.07%), which resulted in two cases of condyloma, two cases of intra-epithelial neoplasia (PIN) I, one case of PIN II, and eight cases of normal tissue. The high-risk HPV test demonstrated 80% sensitivity, 100% specificity, 100% positive predictive value, and 88.9% negative predictive value for the identification of penile lesions. There was a greater chance of finding HPV lesions in the biopsy in the positive cases of high-risk HPV with abnormal peniscopy (p=0.007); OR=51 (CI 1.7-1527.1). Among asymptomatic male sexual partners of women with low-grade intra-epithelial squamous lesions, those infected by high-risk HPV have a higher chance of having abnormal penile tissue compared with male partners without that infection.
Subject: Adolescent
Adult
Carcinoma In Situ
Cross-sectional Studies
Dna, Viral
Diagnostic Tests, Routine
Female
Human Papillomavirus 16
Human Papillomavirus 18
Humans
Male
Middle Aged
Papillomavirus Infections
Penile Diseases
Penile Neoplasms
Penis
Prevalence
Sensitivity And Specificity
Sexual Partners
Uterine Cervical Neoplasms
Rights: fechado
Identifier DOI: 10.1016/j.ejogrb.2006.12.026
Address: http://www.ncbi.nlm.nih.gov/pubmed/17485158
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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